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个人简介
As a PhD student, I was the first to discover that mutations in the caveolin-3 gene are the cause of a novel form of limb-girdle muscular dystrophy, named LGMD-1C. Later on in my career, I developed an interest in breast cancer and I have applied the knowledge and expertise gained from studying mitochondrial metabolism to the breast cancer field.
The main focus of my research is to study the role of the tumor microenvironment in cancer. Specifically, the main theme is elucidating how metabolic alterations in the tumor microenvironment affect tumor growth. We have also provided genetic evidence that enhanced glycolysis in stromal cells supports tumorigenesis.
Another line of research is related to the metabolic requirements of tumor-initiating cells and the repositioning of FDA-approved drugs for their targeting.
Memberships
Fellow, Fellow, The Higher Education Academy, UK (2017)
Member, Editorial Board of the American Journal of Pathology
Member, American Society of Investigative Patholog
The main focus of my research is to study the role of the tumor microenvironment in cancer. Specifically, the main theme is elucidating how metabolic alterations in the tumor microenvironment affect tumor growth. We have also provided genetic evidence that enhanced glycolysis in stromal cells supports tumorigenesis.
Another line of research is related to the metabolic requirements of tumor-initiating cells and the repositioning of FDA-approved drugs for their targeting.
Memberships
Fellow, Fellow, The Higher Education Academy, UK (2017)
Member, Editorial Board of the American Journal of Pathology
Member, American Society of Investigative Patholog
研究兴趣
论文共 312 篇作者统计合作学者相似作者
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Casey Trimmer,Diana Whitaker-Menezes,Gloria Bonuccelli, Janet N. Milliman, Kristin M. Daumer,Andrew E. Aplin,Richard G. Pestell,Federica Sotgia,Michael P. Lisanti,Franco Capozza
crossref(2023)
Casey Trimmer,Diana Whitaker-Menezes,Gloria Bonuccelli, Janet N. Milliman, Kristin M. Daumer,Andrew E. Aplin,Richard G. Pestell,Federica Sotgia,Michael P. Lisanti,Franco Capozza
crossref(2023)
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Agingno. 21 (2023): 11764-11781
Marco Fiorillo,Elena Ricci, Mariarosa Fava, Camilla Longobucco,Federica Sotgia,Pietro Rizza,Marilena Lanzino,Daniela Bonofiglio,Francesca Luisa Conforti,Stefania Catalano,Ines Barone,Catia Morelli,
CELLSno. 24 (2023)
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