Fabian is developing mathematical models of the YAP/TAZ regulating pathway to study how mechanical and molecular stimuli are integrated by cells to mediate their responses. Moreover, he is interested in understanding how the subcellular localisation of signalling molecules affects the outcome of signal integration. This is of importance far beyond mechanosensing pathways, as almost all pathways involve subcellular localisation of at least some important molecules, such as those binding to the cell membrane. This can be especially important when cells change their shapes, and thus the region of membrane/cytosol interactions changes. Consequently, otherwise identical cells with different shapes can behave differently, simply because of their altered geometry.