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个人简介
Our unit is studying vertebrate nervous system development, focusing on the molecular mechanisms that control the transition from neural stem cell to neurons in the developing vertebrate nervous system. We focus on some transcription factors to probe the molecular mechanisms controling neural progenitor maintenance, differentiation, and the generation of neuronal diversity in the developing central and peripheral nervous system. We use for our work the Xenopus embryo, which offers many advantages for in vivo gene function analysis during early embryonic development. Functional assays in Xenopus are complemented by gain- and loss-of-function by electroporation in chick embryos and genetic knockouts in the mouse, to gain fuller understanding of gene action and their normal requirements in the developing embryo. Gaining insight into the mechanisms driving the differentiation of neural stem cells into specific types of neurons will help to understand neurological disorders and to devise novel therapeutic strategies.
研究兴趣
论文共 133 篇作者统计合作学者相似作者
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Xueyi Shen, Jithu Anirudhan,Ambrin Fatima, Tünde Szemes,Marc Keruzore,Estelle Plant,Alba Sabaté San José,Sadia Kricha, Louis-Paul Delhaye, Bilal Ahmad Mian, Lubaba Bintee Khalid, Farhan Ali, Hijab Zahra, Asmat Ali,Mathias Toft,Marc Dieu,Carine Van Lint,Younes Achouri,Patricia Renard, Zafar Iqbal,Eric Bellefroid
crossref(2024)
biorxiv(2024)
Jithu Anirudhan, Xueyi Shen, Tünde Szemes,Marc Dieu,Abdulkader Azouz,Louise Conrard,Gilles Doumont,Maren Sitte,Younes Achouri,Sadia Kricha,Gabriela Salinas-Riester,Patricia Renard,Eric J. Bellefroid
crossref(2024)
Maud Martin,Simon Vermeiren,Naguissa Bostaille,Marie Eubelen,Daniel Spitzer,Marjorie Vermeersch,Caterina P. Profaci, Elisa Pozuelo,Xavier Toussay,Joanna Raman-Nair,Patricia Tebabi,Michelle America,Aurelie De Groote,Leslie E. Sanderson,Pauline Cabochette,Raoul F. Germano,David Torres,Sebastien Boutry,Alban de Kerchove D'Exaerde,Eric J. Bellefroid,Timothy N. Phoenix,Kavi Devraj,Baptiste Lacoste,Richard Daneman,Stefan Liebner,Benoit Vanhollebeke
Jonathan Delhermite,Lionel Tafforeau,Sunny Sharma,Virginie Marchand,Ludivine Wacheul, Ruben Lattuca,Simon Desiderio,Yuri Motorin,Eric Bellefroid,Denis L. J. Lafontaine
PLoS Geneticsno. 1 (2022): e1010012-e1010012
The Neurobiology, Physiology, and Psychology of Painpp.23-31, (2022)
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作者统计
#Papers: 130
#Citation: 3407
H-Index: 33
G-Index: 50
Sociability: 7
Diversity: 3
Activity: 34
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