Su Enming J

Torrente D, Su EJ, Fredriksson L, Warnock M, Bushart D, Mann KM, Emal CD, Lawrence DA. Compartmentalized Actions of the Plasminogen Activator Inhibitors, PAI-1 and Nsp, in Ischemic Stroke. Transl Stroke Res. 2022 Feb 4;. doi: 10.1007/s12975-022-00992-y. [Epub ahead of print] PubMed PMID: 35122213. Aamir R, Fyffe C, Korin N, Lawrence DA, Su EJ, Kanapathipillai M. Heparin and Arginine Based Plasmin Nanoformulation for Ischemic Stroke Therapy. Int J Mol Sci. 2021 Oct 25;22(21). doi: 10.3390/ijms222111477. PubMed PMID: 34768908; PubMed Central PMCID: PMC8584024. Reinke AA, Li SH, Warnock M, Shaydakov ME, Guntaka NS, Su EJ, Diaz JA, Emal CD, Lawrence DA. Dual-reporter high-throughput screen for small-molecule in vivo inhibitors of plasminogen activator inhibitor type-1 yields a clinical lead candidate. J Biol Chem. 2019 Feb 1;294(5):1464-1477. doi: 10.1074/jbc.RA118.004885. Epub 2018 Dec 3. PubMed PMID: 30510136; PubMed Central PMCID: PMC6364767. Wang J, Su E, Wang H, Guo C, Lawrence DA, Eitzman DT. Traumatic Brain Injury Leads to Accelerated Atherosclerosis in Apolipoprotein E Deficient Mice. Sci Rep. 2018 Apr 4;8(1):5639. doi: 10.1038/s41598-018-23959-2. PubMed PMID: 29618740; PubMed Central PMCID: PMC5884790. Su EJ, Cao C, Fredriksson L, Nilsson I, Stefanitsch C, Stevenson TK, Zhao J, Ragsdale M, Sun YY, Yepes M, Kuan CY, Eriksson U, Strickland DK, Lawrence DA, Zhang L. Microglial-mediated PDGF-CC activation increases cerebrovascular permeability during ischemic stroke. Acta Neuropathol. 2017 Oct;134(4):585-604. doi: 10.1007/s00401-017-1749-z. Epub 2017 Jul 19. PubMed PMID: 28725968; PubMed Central PMCID: PMC5587628. Xiang J, Tang Y, Li C, Su EJ, Lawrence DA, Keep RF. Mechanisms Underlying Astrocyte Endfeet Swelling in Stroke. Acta Neurochir Suppl. 2016;121:19-22. doi: 10.1007/978-3-319-18497-5_4. Review. PubMed PMID: 26463917. Su EJ, Fredriksson L, Kanzawa M, Moore S, Folestad E, Stevenson TK, Nilsson I, Sashindranath M, Schielke GP, Warnock M, Ragsdale M, Mann K, Lawrence AL, Medcalf RL, Eriksson U, Murphy GG, Lawrence DA. Imatinib treatment reduces brain injury in a murine model of traumatic brain injury. Front Cell Neurosci. 2015;9:385. doi: 10.3389/fncel.2015.00385. eCollection 2015. PubMed PMID: 26500491; PubMed Central PMCID: PMC4596067. Fredriksson L, Stevenson TK, Su EJ, Ragsdale M, Moore S, Craciun S, Schielke GP, Murphy GG, Lawrence DA. Identification of a neurovascular signaling pathway regulating seizures in mice. Ann Clin Transl Neurol. 2015 Jul;2(7):722-38. doi: 10.1002/acn3.209. Epub 2015 May 1. PubMed PMID: 26273685; PubMed Central PMCID: PMC4531055. Su EJ, Lawrence DA. α2 Antiplasmin and microvascular thrombosis in ischemic stroke. Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2522-3. doi: 10.1161/ATVBAHA.114.304616. PubMed PMID: 25411105. Luo W, Su EJ, Wang J, Wang H, Guo C, Pawar A, Campbell AD, Lawrence DA, Eitzman DT. Increased stroke size following MCA occlusion in a mouse model of sickle cell disease. Blood. 2014 Mar 20;123(12):1965-7. doi: 10.1182/blood-2014-01-549717. PubMed PMID: 24652968; PubMed Central PMCID: PMC3962170. Sashindranath M, Sales E, Daglas M, Freeman R, Samson AL, Cops EJ, Beckham S, Galle A, McLean C, Morganti-Kossmann C, Rosenfeld JV, Madani R, Vassalli JD, Su EJ, Lawrence DA, Medcalf RL. The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans. Brain. 2012 Nov;135(Pt 11):3251-64. doi: 10.1093/brain/aws178. Epub 2012 Jul 20. PubMed PMID: 22822039; PubMed Central PMCID: PMC3501968. Frieler RA, Ray JJ, Meng H, Ramnarayanan SP, Usher MG, Su EJ, Berger S, Pinsky DJ, Lawrence DA, Wang MM, Mortensen RM. Myeloid mineralocorticoid receptor during experimental ischemic stroke: effects of model and sex. J Am Heart Assoc. 2012 Oct;1(5):e002584. doi: 10.1161/JAHA.112.002584. Epub 2012 Oct 25. PubMed PMID: 23316294; PubMed Central PMCID: PMC3541615. Su EJ, Lawrence DA. The functional dissonance of platelets. Blood. 2012 Aug 9;120(6):1154-5. doi: 10.1182/blood-2012-05-427450. PubMed PMID: 22879626. Lawrence DA, Su EJ, Petersen KU. Thrombomodulin and the brain: past, present, and future. Neurology. 2012 Apr 17;78(16):1280-1. doi: 10.1212/01.wnl.0000414240.34236.2c. PubMed PMID: 22508851. Fredriksson L, Nilsson I, Su EJ, Andrae J, Ding H, Betsholtz C, Eriksson U, Lawrence DA. Platelet-derived growth factor C deficiency in C57BL/6 mice leads to abnormal cerebral vascularization, loss of neuroependymal integrity, and ventricular abnormalities. Am J Pathol. 2012 Mar;180(3):1136-1144. doi: 10.1016/j.ajpath.2011.12.006. Epub 2012 Jan 9. PubMed PMID: 22230248; PubMed Central PMCID: PMC3349890. Su EJ, Geyer M, Wahl M, Mann K, Ginsburg D, Brohmann H, Petersen KU, Lawrence DA. The thrombomodulin analog Solulin promotes reperfusion and reduces infarct volume in a thrombotic