Dwight V Nissley - Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc

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论文共 102 篇作者统计合作学者相似作者

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Comparative Analysis of KRAS4a and KRAS4b Splice Variants Reveals Distinctive Structural and Functional Properties

Matthew J. Whitley,Timothy H. Tran,Megan Rigby,Ming Yi,Srisathiyanarayanan Dharmaiah,Timothy J. Waybright,Nitya Ramakrishnan, Shelley Perkins,Troy Taylor,Simon Messing,Dominic Esposito,Dwight V. Nissley,Frank McCormick,Andrew G. Stephen,Thomas Turbyville,Gabriel Cornilescu,Dhirendra K. Simanshu

SCIENCE ADVANCESno. 7 (2024)

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Progress in Targeting KRAS Directly

Dwight V. Nissley,Andrew G. Stephen,Ming Yi,Frank McCormick

Methods in Molecular Biology KRAS (2024): 1-12

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Natural Product Graveoline Modulates Kirsten Rat Sarcoma Viral Oncogene Homologue (KRAS) Membrane Association: Insights from Advanced Spectroscopic Studies

Gabriel Cornilescu,Lakshman Bindu,Louise Sternicki,Fa-An Chao,William K. Gillette,Nicole Fer, John Colombus, Jean Castillo, Pedro Andrade Bonilla,Que N. Van, Erik Larsen, Min Hong,William Burgan,Thomas Turbyville,Dwight V. Nissley, Miaomiao Liu,Ronald Quinn,Frantz L. Jean-Francois

ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE（2024）

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Abstract ND07: BBO-8520, a First-in-class, Direct Inhibitor of KRASG12C (ON), Locks GTP-bound KRASG12C in the State 1 Conformation Resulting in Rapid and Complete Blockade of Effector Binding

Anna E. Maciag, James Stice, Bin Wang,Alok Sharma,Albert Chan, Ken Lin, Devansh Singh,Marcin Dyba,Yue Yang, Saman Setoodeh, Brian P. Smith,Dana Rabara, Zuhui Zhang,Erik K. Larsen, Dom Esposito,John Paul Denson,Michela Ranieri,Mary Meynardie,Sadaf Mehdizadeh,Patrick Alexander,Maria Abreu Blanco,David Turner,Rui Xu,Felice C. Lightstone,Kwok Kin Wong,Dhirendra Simanshu,Keshi Wang,Andrew G. Stephen,Kerstin Sinkevicius,Dwight V. Nissley,Eli Wallace,Frank McCormick,Pedro J. Beltran

Cancer Researchno. 7_Supplement (2024)

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A Top-Down Proteomic Assay to Evaluate KRAS4B-compound Engagement

Robert A. D'Ippolito,Dana Rabara,Maria Abreu Blanco, Emily Alberico,Matthew R. Drew,Nitya Ramakrishnan, Dara Sontan,Stephanie R. T. Widmeyer, Grace M. Scheidemantle,Simon Messing,David Turner,Michelle Arkin,Anna E. Maciag,Andrew G. Stephen,Dominic Esposito,Frank Mccormick,Dwight V. Nissley,Caroline J. Dehart

ANALYTICAL CHEMISTRY（2024）

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Revealing the Mechanism of Action of a First-in-class Covalent Inhibitor of KRASG12C (ON) and Other Functional Properties of Oncogenic KRAS by 31P NMR

Alok K. Sharma, Jun Pei,Yue Yang,Marcin Dyba,Brian Smith,Dana Rabara,Erik Larsen,Felice C. Lightstone,Dominic Esposito,Andrew G. Stephen, Bin Wang,Pedro J. Beltran,Eli Wallace,Dwight V. Nissley,Frank McCormick,Anna E. Maciag

Journal of Biological Chemistrypp.105650, (2024)

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Abstract RF02-02: BBO-10203, a first-in-class, orally bioavailable, selective covalent small molecule that inhibits RAS-driven PI3Kalpha activity without affecting glucose metabolism

Pedro Beltran,Simanshu Dhirendra,Rui Xu, Ming Chen, Daniel Czyzyk, Sofia Donovan, Siyu Feng, Cindy Feng, Lijuan Fu,Felice Lightstone, Ken Lin,Anna Maciag,Dwight Nissley, Erin Riegler,Kerstin Sinkevicius,Andrew Stephen, James Stice,David Turner,Bin Wang,Keshi Wang,Yue Yang, Cathy Zhang,Frank McCormick,Eli Wallace

Cancer Researchno. 9_Supplement (2024): RF02-02

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Structural Dynamics of RAF1-HSP90-CDC37 and HSP90 Complexes Reveal Asymmetric Client Interactions and Key Structural Elements

Lorenzo I. Finci,Mayukh Chakrabarti,Gulcin Gulten,Joseph Finney,Carissa Grose,Tara Fox,Renbin Yang,Dwight V. Nissley,Frank McCormick,Dominic Esposito,Trent E. Balius,Dhirendra K. Simanshu

Communications Biologyno. 1 (2024)

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