Dorothee L. Berthold - ETH Zurich | 人才画像

基本信息

Career Trajectory

Bio

I’m fascinated by the complex immune microenvironment in the gut and how the immune system tackles the challenge of remaining unresponsive to the commensal microflora and food antigens whilst being able to mount a rapid immune response upon facing pathogens. The importance of maintaining gut homeostasis and tight control of immune response is emphasized in the context of chronic auto-inflammatory bowel diseases like Crohn’s disease and ulcerative colitis.

Research Interests

Papers共 15 篇Author StatisticsCo-AuthorSimilar Experts

By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选

Macrophages in the Synovial Lining Niche Initiate Neutrophil Recruitment and Articular Inflammation

Kristina Zec,Barbora Schonfeldova,Zhichao Ai,Erinke Van Grinsven,Gabriela Pirgova,Hayley L. Eames,Dorothee L. Berthold,Moustafa Attar,Ewoud B. Compeer,Tal I. Arnon,Irina A. Udalova

The Journal of Experimental Medicineno. 8 (2023)

Cited0Views0WOSBibtex

Intercrypt sentinel macrophages induce a tunable antibacterial NFB response in intestinal epithelial cells via TNF

A. Hausmann, B. Felmy, L. Kunz, S. Kroon,D. L. Berthold, G. Ganz, I Sandu, T. Nakamura, N. Zangger, Y. Zhang, T. Dolowschiak,S. A. Fattinger, M. Furter, Hauser A. A. Mueller, M. Barthel,K. Vlantis,L. Wachsmuth,J. Kisielow,L. Tortola, D. Heide,M. Heikenwaelder,A. Oxenius,M. Kopf, T. Schroeder,M. Pasparakis,M. E. Sellin,W-D Hardt

EUROPEAN JOURNAL OF IMMUNOLOGY (2022): 120-120

Cited0Views0Bibtex

Defactinib Inhibits PYK2 Phosphorylation of IRF5 and Reduces Intestinal Inflammation

Grigory Ryzhakov,Hannah Almuttaqi,Alastair L. Corbin,Dorothee L. Berthold,Tariq Khoyratty,Hayley L. Eames,Samuel Bullers,Claire Pearson,Zhichao Ai,Kristina Zec,Sarah Bonham,Roman Fischer,Luke Jostins-Dean,Simon P. L. Travis,Benedikt M. Kessler,Irina A. Udalova

Nature Communications（2021）

Cited12Views0WOSNATUREBibtex

Intercrypt sentinel macrophages tune antibacterial NF-B responses in gut epithelial cells via TNF

Annika Hausmann,Boas Felmy,Leo Kunz,Sanne Kroon,Dorothee Lisa Berthold, Giverny Ganz,Ioana Sandu, Toshihiro Nakamura,Nathan Sebastien Zangger, Yang Zhang,Tamas Dolowschiak,Stefan Alexander Fattinger,Markus Furter, Anna Angelika Mueller-Hauser,Manja Barthel,Katerina Vlantis,Laurens Wachsmuth,Jan Kisielow, Luigi Tortola,Danijela Heide,Mathias Heikenwaelder, Annette Oxenius, Manfred Kopf,Timm Schroeder,Manolis Pasparakis,Mikael Erik Sellin,Wolf-Dietrich Hardt

JOURNAL OF EXPERIMENTAL MEDICINEno. 11 (2021)

Cited0Views0Bibtex

Regional Specialization of Macrophages along the Gastrointestinal Tract

Dorothée L Berthold,Kelsey D J Jones,Irina A Udalova

Trends in immunologyno. 9 (2021): 795-806

Cited9Views0WOSBibtex

Intestinal Epithelial NAIP/NLRC4 Restricts Systemic Dissemination of the Adapted Pathogen Salmonella Typhimurium Due to Site-Specific Bacterial PAMP Expression

Annika Hausmann,Desirée Böck,Petra Geiser,Dorothée L. Berthold,Stefan A. Fattinger,Markus Furter,Judith A. Bouman,Manja Barthel-Scherrer, Crispin M. Lang,Erik Bakkeren, Isabel Kolinko,Médéric Diard,Dirk Bumann,Emma Slack,Roland R. Regoes,Martin Pilhofer,Mikael E. Sellin,Wolf-Dietrich Hardt

Mucosal Immunology（2020）

Cited89Views0WOSNATUREBibtex

PYK2 controls intestinal inflammation via activation of IRF5 in macrophages

Grigory Ryzhakov,Hannah Almuttaqi,Alastair L. Corbin,Tariq Khoyratty,Dorothee Berthold,Samuel Bullers,Hayley L Eames,Zhichao Ai,Sarah Bonham,Roman Fischer,Luke Jostins-Dean,Simon P.L. Travis,Benedikt M. Kessler,Irina A. Udalova

biorxiv（2020）

Cited0Views0Bibtex

IRF5 Guides Monocytes Toward an Inflammatory CD11c+ Macrophage Phenotype and Promotes Intestinal Inflammation

Alastair L. Corbin,Maria Gomez-Vazquez,Dorothee L. Berthold,Moustafa Attar,Isabelle C. Arnold,Fiona M. Powrie,Stephen N. Sansom,Irina A. Udalova

Science Immunology（2020）

Cited45Views0WOSSCIENCEBibtex

Author Statistics

Co-Author

Co-Institution

D-Core

合作者
学生
导师

No result temporarily, you can search similar Scholar with the same research interest

Data Disclaimer

The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn