Dirk Nagorsen - Early Dev Hematol & Oncol, Amgen Inc

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662 A Phase1 Study of Autologous Engineered CD4+ and CD8+ T Cells, HLA-A*11:01-restricted, KRAS G12V-specific, Transgenic TCR; CD8α/β Coreceptor and a FAS41BB Switch Receptor in Patients with Solid Tumors

Shaunica Mitchell, Binaish Khan,Francis Payumo, E Gabriela Chiorean,Zhubin Gahvari, J Randolph Hecht,Michael Hurwitz,Rom S Leidner, Heinz-Josef Lenz,Meredith Pelster, Adam J Schoenfeld,Salman R Punekar,Dan Zhao, Soumit Basu,Dirk Nagorsen

Regular and Young Investigator Award Abstracts (2024)

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Correlation of Allele-Specific HLA Loss of Heterozygosity in Patients with Cancer with Driver Mutations

Christian Roy,Tomasz Sewastianik,Patrick Halvey,Meagan Montesion,Aastha Jindal,Markus Vallaster,Hubert Lam, Sean Garrity,Gary Shapiro,Christopher A. Klebanoff,Loic Vincent,Greg Opiteck,Dirk Nagorsen

MOLECULAR THERAPYno. 4 (2024): 392-392

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AFNT-211: A Phase 1 Study of Autologous CD4+and CD8+T Cells Engineered to Express a High Avidity HLA-A*11:01-restricted, KRAS G12V-specific, Transgenic TCR, a CD8α/β Coreceptor, and a FAS41BB Switch Receptor in Patients with Advanced/metastatic Solid Tumors

Shaunica Mitchell, Binaish Khan,Francis Payumo,E. Gabriela Chiorean,Zhubin Gahvari, J. Randolph Hecht,Michael E. Hurwitz,Rom Leidner, Heinz-Josef Lenz,Meredith Pelster,Salman Rafi Punekar, Adam Jacob Schoenfeld,Dan Zhao,Markus P. Vallaster,Dirk Nagorsen

JOURNAL OF CLINICAL ONCOLOGYno. 16 (2024)

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AFNT-211: A phase1 study of autologous CD4+and CD8+T cells engineered to express a high avidity HLA-A*11:01-restricted, KRAS G12V-specific, transgenic TCR; CD8α/β coreceptor; and a FAS41BB switch receptor in patients with advanced/metastatic solid tumors

Shaunica Mitchell, Binaish Khan,Francis Payumo,E. Gabriela Chiorean,Zhubin Gahvari,J. Randolph Hecht, Michael Hurwitz,Rom Leidner,Heinz-Josef Lenz,Meredith Pelster,Salman Punekar,Adam Schoenfeld, Dan Zhao,Markus Vallaster,Dirk Nagorsen

CANCER RESEARCHno. 7 (2024)

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Abstract CT076: AFNT-211: A phase1 study of autologous CD4+ and CD8+ T cells engineered to express a high avidity HLA-A*11:01-restricted, KRAS G12V-specific, transgenic TCR; CD8α/β coreceptor; and a FAS41BB switch receptor in patients with advanced/metastatic solid tumors

Shaunica Mitchell, Binaish Khan,Francis Payumo,E. Gabriela Chiorean,Zhubin Gahvari,J. Randolph Hecht,Michael Hurwitz,Rom Leidner,Heinz-Josef Lenz,Meredith Pelster,Salman Punekar,Adam Schoenfeld, Dan Zhao,Markus Vallaster,Dirk Nagorsen

Cancer Researchno. 7_Supplement (2024)

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AFNT-211: A Phase 1 Study of Autologous CD4+ and CD8+ T Cells Engineered to Express a High Avidity HLA-A*11:01-restricted, KRAS G12V-specific, Transgenic TCR, a CD8α/β Coreceptor, and a FAS41BB Switch Receptor in Patients with Advanced/metastatic Solid Tumors

Scott A. Mitchell, Badshah Khan,Francis Payumo,E. Gabriela Chiorean,Zhubin Gahvari,J. Randolph Hecht,Michael Hurwitz,Rom S. Leidner,Heinz‐Josef Lenz,Meredith S. Pelster,Salman R. Punekar,Adam J. Schoenfeld,Dan Zhao,Markus Vallaster,Dirk Nagorsen

Journal of clinical oncologyno. 16_suppl (2024): TPS8650-TPS8650

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Abstract CT076: AFNT-211: A Phase1 Study of Autologous CD4+ and CD8+ T Cells Engineered to Express a High Avidity HLA-A*11:01-restricted, KRAS G12V-specific, Transgenic TCR; CD8α/β Coreceptor; and a FAS41BB Switch Receptor in Patients with Advanced/metastatic Solid Tumors

Scott A. Mitchell, Binaish Khan,Francis Payumo,E. Gabriela Chiorean,Zhubin Gahvari,J. Randolph Hecht,Michael E. Hurwitz,Rom S. Leidner, Heinz‐Josef Lenz,Meredith S. Pelster,Salman R. Punekar, Adam J. Schoenfeld,Dan Zhao,Markus Vallaster,Dirk Nagorsen

Cancer Researchno. 7_Supplement (2024): CT076-CT076

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AFNT-211: an FAS-41BB–enhanced TCR-T Cell Therapy with Stem-Like Properties Targeting KRAS G12V-expressing Solid Tumors

Michele Hoffmann,Lauren Brown,Martin Campbell,Klaus Pechhold,Xingyue He, Joseph Lee,Hongjing Qu,Jinsheng Liang,Aude Chapuis,Philip D. Greenberg,Dirk Nagorsen,Markus P. Vallaster,Martina Canestraro,Hubert Lam,Gary Shapiro,Damien Hallet,Kim Nguyen,Loic Vincent,Thomas Schmitt

JOURNAL OF CLINICAL ONCOLOGYno. 16 (2023)

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First-in-Human Study of AMG 820, a Monoclonal Anti-Colony-Stimulating Factor 1 Receptor Antibody, in Patients with Advanced Solid Tumors

Kyriakos P. Papadopoulos,Larry Gluck,Lainie P. Martin,Anthony J. Olszanski,Anthony W. Tolcher,Gataree Ngarmchamnanrith,Erik Rasmussen,Benny M. Amore,Dirk Nagorsen,John S. Hill,Joe Stephenson

openalex（2023）

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