Diego Gonzalez Cabrera - Drug Discovery and Development Centre (H3D), University of Cape Town

基本信息

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职业迁徙

个人简介

Experienced synthetic and medicinal chemist in the drug discovery sector for more than 10 years both in South Africa and Europe. Committed to innovative and high-quality drug discovery and its translation into lifesaving treatments.

研究兴趣

论文共 29 篇作者统计合作学者相似作者

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Analysis of the Physicochemical Properties of Anti-Schistosomal Compounds to Identify Next-Generation Leads

Diego Gonzalez Cabrera,Jennifer Keiser,Thomas Spangenberg

ACS MEDICINAL CHEMISTRY LETTERS（2024）

引用0浏览0WOS引用

Anti-infectives Developed As Racemic Drugs in the 21st Century: Norm or Exception

Diego González Cabrera,Dennis A Smith,Gregory S Basarab,James Duffy,Thomas Spangenberg,Kelly Chibale

ACS medicinal chemistry lettersno. 7 (2023): 875-878

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Plasmodial Kinase Inhibitors: License to Cure

Diego Gonzalez Cabrera,Andre Horatscheck,Colin R. Wilson,Greg Basarab,Charles J. Eyermann,Kelly Chibale

Journal of medicinal chemistry（2018）

引用49浏览0WOS引用

UCT943, a Next-Generation Plasmodium Falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria

Antimicrobial agents and chemotherapy（2018）

引用51浏览0WOS引用

Potent Plasmodium Falciparum Gametocytocidal Compounds Identified by Exploring the Kinase Inhibitor Chemical Space for Dual Active Antimalarials

The journal of antimicrobial chemotherapy/Journal of antimicrobial chemotherapyno. 5 (2018): 1279-1290

引用19浏览0WOS引用

Identification, Characterization, and Optimization of 2,8-Disubstituted-1,5-naphthyridines As Novel Plasmodium Falciparum Phosphatidylinositol-4-kinase Inhibitors with in Vivo Efficacy in a Humanized Mouse Model of Malaria

Nishanth Kandepedu,Diego Gonzalez Cabrera, Srinivas Eedubilli,Dale Taylor,Christel Brunschwig,Liezl Gibhard,Mathew Njoroge,Nina Lawrence,Tanya Paquet,Charles J. Eyermann,Thomas Spangenberg,Gregory S. Basarab,Leslie J. Street,Kelly Chibale

Journal of medicinal chemistry（2018）

引用30浏览0WOS引用

UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria (vol 62, e00012-18, 2018

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY（2018）

引用51浏览0WOS引用

Antimalarial Efficacy of MMV390048, an Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase

Tanya Paquet,Claire Le Manach,Diego Gonzalez Cabrera,Yassir Younis,Philipp P. Henrich,Tara S. Abraham,Marcus C. S. Lee,Rajshekhar Basak,Sonja Ghidelli-Disse,Maria Jose Lafuente-Monasterio,Marcus Bantscheff,Andrea Ruecker,Andrew M. Blagborough,Sara E. Zakutansky,Anne-Marie Zeeman,Karen L. White,David M. Shackleford,Janne Mannila,Julia Morizzi,Christian Scheurer,Inigo Angulo-Barturen,Maria Santos Martinez,Santiago Ferrer,Laura Maria Sanz,Francisco Javier Gamo,Janette Reader,Mariette Botha,Koen J. Dechering,Robert W. Sauerwein,Anchalee Tungtaeng,Pattaraporn Vanachayangkul,Chek Shik Lim,Jeremy Burrows,Michael J. Witty,Kennan C. Marsh,Christophe Bodenreider,Rosemary Rochford,Suresh M. Solapure, Mara Belen Jimenez-Diaz,Sergio Wittlin,Susan A. Charman,Cristina Donini,Brice Campo,Lyn-Marie Birkholtz,Kirsten K. Hanson,Gerard Drewes,Clemens H. M. Kocken,Michael J. Delves,Didier Leroy,David A. Fidock,David Waterson,Leslie J. Street,Kelly Chibale

Science translational medicine（2017）

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