Research:
The Bowie Lab studies the two major neurotransmitter receptors of the brain, namely ionotropic glutamate receptors and GABA-A receptors. Both receptor families are widespread in the vertebrate brain and fulfill many important roles in healthy individuals as well as being implicated in disease states (e.g. autism, epilepsy, Alzheimer's disease). These receptors are studied to understand how they shape neuronal circuit behaviour and how they may be targeted to treat CNS disease.