My focus is directed toward investigating the pathology of malfunctioning inhibitory cortical circuits associated with mental illnesses such as bipolar disorder and schizophrenia. To examine and isolate specific GABA-ergic interneuron subtypes in postmortem brain, I utilize gene expression analyses as well as implement neuroanatomical techniques including fluorescent in situ hybridization, brain transparency methods (e.g., CLARITY, iDISCO), and lightsheet microscopy.