David J Huggins

基本信息

浏览量：22

职业迁徙

个人简介

暂无内容

研究兴趣

论文共 70 篇作者统计合作学者相似作者

按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选

Addition to “scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation”

Sheng Sun,Makoto Fushimi,Thomas Rossetti,Navpreet Kaur,Jacob Ferreira,Michael Miller,Jonathan Quast,Joop van den Heuvel,Clemens Steegborn, Lonny R. Levin,Jochen Buck,Robert W. Myers,Stacia Kargman,Nigel J. Liverton,Peter T. Meinke,David J. Huggins

Journal of chemical information and modelingno. 3 (2024): 1106-1106

引用0浏览0引用

The Benefits of Translating Biomedical Research at Drug Discovery Institutes

David J Huggins,Jonathan Baell, Paul E Brennan, Alex Burgin,Duncan E Scott

Nature reviews Drug discovery (2024)

引用0浏览0WOSNATURE引用

Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable in Vivo Studies: Discovery of TDI-11055

Mayako Michino,Tanweer A. Khan,Michael W. Miller,Yoshiyuki Fukase,Jeremie Vendome,Carolina Adura,J. Fraser Glickman,Yiman Liu,Liling Wan,C. David Allis,Andrew W. Stamford,Peter T. Meinke,Louis M. Renzetti,Stacia Kargman, Nigel J. Liverton,David J. Huggins

ACS MEDICINAL CHEMISTRY LETTERSno. 4 (2024): 524-532

引用0浏览0WOS引用

Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior

Emely V. Zeledon, Leigh A. Baxt,Tanweer A. Khan,Mayako Michino,Michael Miller,David J. Huggins,Caroline S. Jiang,Leslie B. Vosshall,Laura B. Duvall

PARASITES & VECTORSno. 1 (2024)

引用0浏览0WOS引用

Indazole to 2‐cyanoindole Scaffold Progression for Mycobacterial Lipoamide Dehydrogenase Inhibitors Achieves Extended Target Residence Time and Improved Antibacterial Activity

Shan Sun,John Ginn,Tomasz Kochanczyk,Nancy Arango,Xiuju Jiang,David J Huggins,James Bean,Mayako Michino,Leigh Baxt,Nigel Liverton,Peter T Meinke,Ruslana Bryk

Angewandte Chemie (International ed in English)no. 44 (2024): e202407276-e202407276

引用0浏览0WOS引用

BAT2: an Open-Source Tool for Flexible, Automated and Low Cost Absolute Binding Free Energy Calculations

Germano Heinzelmann,David J. Huggins,Michael K. Gilson

Journal of Chemical Theory and Computationno. 15 (2024): 6518-6530

引用0浏览0WOS引用

On-demand Male Contraception Via Acute Inhibition of Soluble Adenylyl Cyclase

Melanie Balbach,Thomas Rossetti,Jacob Ferreira,Lubna Ghanem,Carla Ritagliati,Robert W. Myers,David J. Huggins,Clemens Steegborn,Ileana C. Miranda,Peter T. Meinke,Jochen Buck,Lonny R. Levin

Nature Communications（2023）

引用11浏览0WOSNATURE引用

Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation

Shan Sun,Makoto Fushimi,Thomas Rossetti,Navpreet Kaur,Jacob Ferreira,Michael Miller,Jonathan Quast,Joop van den Heuvel,Clemens Steegborn,Lonny R. Levin,Jochen Buck,Robert W. Myers,Stacia Kargman, Nigel Liverton,Peter T. Meinke,David J. Huggins

Journal of chemical information and modelingno. 9 (2023): 2828-2841

引用0浏览0WOSEI引用

Shape-Based Virtual Screening of a Billion-Compound Library Identifies Mycobacterial Lipoamide Dehydrogenase Inhibitors

Mayako Michino,Alexandre Beautrait,Nicholas A. Boyles, Aparna Nadupalli,Alexey Dementiev,Shan Sun,John Ginn,Leigh Baxt,Robert Suto,Ruslana Bryk,Steven V. Jerome,David J. Huggins,Jeremie Vendome

ACS bio & med chem auno. 6 (2023): 507-515

引用0浏览0WOS引用

Enhancing Hit Discovery in Virtual Screening Through Absolute Protein-Ligand Binding Free-Energy Calculations

Wei Chen,Di Cui,Steven V. Jerome,Mayako Michino,Eelke B. Lenselink,David J. Huggins,Alexandre Beautrait,Jeremie Vendome,Robert Abel,Richard A. Friesner,Lingle Wang

Journal of chemical information and modelingno. 10 (2023): 3171-3185

引用12浏览0WOSEI引用

加载更多

作者统计

合作学者

合作机构

D-Core

合作者
学生
导师

暂无相似学者，你可以通过学者研究领域进行搜索筛选

数据免责声明

页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果，我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问，可以通过电子邮件方式联系我们：report@aminer.cn

助理教授

论文共 70 篇作者统计合作学者相似作者