Research Interests
My lab studies the molecular events involved in the battle between host and pathogens, in particular between RNA viruses and humankind. Using various methods ranging from biochemistry, biophysics, structural biology, and cell biology, we successfully answered interesting and demanding questions in the fields of viral replication and host defense systems. Our long-term goal is to better understand the conflict between host and pathogens and improve the well-being of humankind. My lab’s research focuses on the following two interrelated directions: 1) RNA virus transcription, replication, and the generation of pathogenic RNA species; 2) Host defense mechanisms involved in pathogenic RNA sensing and processing. We would like to exercise molecular engineering targeting RNA and RNA-protein complexes to develop new methods and tools for research and therapies.