His research interests involve the heteroepitaxial growth and characterization of oxide thin films by reactive molecular-beam epitaxy (MBE), especially utilizing a 'materials-by-design' approach to the discovery of materials with properties superior to any known. His group synthesizes these oxide heterostructures using molecular-beam epitaxy (MBE). He has published over 700 papers and 12 patents resulting in an h-index of 94 and over 46,000 citations. His work has been recognized by the highest awards for materials discovery by four relevant societies: the MRS Medal from the Materials Research Society, the Frank Prize from the International Organization for Crystal Growth, the McGroddy Prize from the American Physical Society, and the John A. Thornton Memorial Award/Lecture from the American Vacuum Society. He is a Fellow of the American Physical Society, the Materials Research Society, the American Vacuum Society, and is a member of the National Academy of Engineering.