Clooney C. Y. Cheng

Clooney’s research focuses on the epigenomic landscape of transposable elements (TEs) in hepatocellular carcinoma (HCC), the sixth most common cancer and the fourth leading cause of cancer-related mortality worldwide. Integrating multi-omics datasets and functional experiments, Clooney attempts to (1) elucidate the transcriptional regulatory role of TEs in hepatocarcinogenesis, (2) establish the clinical relevance of regulatory TEs and (3) evaluate the therapeutic potentials of targeting TEs