Claudina Rodrigues-Pousada

Our laboratory works in the mechanisms involved in homeostasis control when yeast cells are exposed to different environmental cues, in particular to arsenic and iron overload. Yap transcription factors are involved in stress response of which Yap8 is responsible for As detoxification enzymes whereas Yap1contributes to As stress response by regulating the expression of Ycf1, involved in the vacuolar As detoxification process.Also it was identified a new route for Cd++ detoxification.