Dr. Caldarone specializes in the management of children and adults with congenital heart disease. His main clinical interests include the treatment of left ventricular outflow tract obstruction, coronary anomalies, and pulmonary vein stenosis.

Dr. Caldarone’s research interests include the role of apoptosis related mitochondrial dysfunction and remote ischemic preconditioning as mediators of reperfusion injury. Most recently, Dr. Caldarone has focused on pulmonary vein stenosis and tissue engineering of pulmonary valves.