Prof. Hsu’s research interests include electronic medical/health record, clinical/hospital information system, medical information standards, biomedical data sharing/processing/analysis, e-health/cloud computing infrastructure, biomedical database and biomedical signal processing. He has been working on various topics of medical informatics for more than twenty years. He has published various articles in The Journal Medical Internet Research, The Journal on Information Technology in Healthcare, Computer Methods and Programs in Biomedicine, PLOS ONE, European Journal of Nuclear Medicine and Molecular Imaging, Methods of Information in Medicine, International Journal of Andrology, Communications in Computer and Information Science, Telemedicine and e-Health, and The Journal of Taiwan Association for Medical Informatics. He was the President of Taiwan Association for Medical Informatics from 2008 to 2011 and from 2019 to 2022, and had served as the Editor in Chief of The Journal of Taiwan Association for Medical Informatics since 2004 to 2007. Professor Hsu is also a member of the board of HL7 Taiwan and Taiwan Association for Nursing Informatics. Prof. Hsu is currently the President of the Taiwan eHealth Association, starting from July 2015.