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个人简介
Research Interests: The research in her laboratory is aimed at identifying novel intracellular and molecular pathways that control the pathogenesis of chronic lung diseases associated with environmental exposures, particularly cigarette smoke. Her main focus is understanding how cigarette smoke-induced inflammation and cell death (apoptosis) are regulated. Chronic and persistent inflammation and the death of lung cells are involved in the etiology of lung diseases such as chronic obstructive pulmonary disease (COPD), which is almost always caused by cigarette smoke (>90% of cases). There is no cure for individuals afflicted with COPD and there are no effective therapies that can reduce disease progression. This is due, in part, to a lack of novel intracellular targets for the development of pharmacological therapies.
研究兴趣
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TOXICOLOGY LETTERS (2024): 13-25
Archives of Toxicologyno. 7 (2023): 1963-1978
Immunology & Cell Biologyno. 2 (2023): 156-170
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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2023)
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Biochemical pharmacology (2023): 115745-115745
Breanne Freeman,Jessica Mamallapalli,Tengfei Bian, Kayleigh Ballas, Allison Lynch, Alexander Scala,Zhiguang Huo,Kristianna M Fredenburg,Adriaan W Bruijnzeel,Carolyn J Baglole,Junxuan Lu,Ramzi G Salloum,
Bayan Alakhtar,Cynthia Guilbert, Nivetha Subramaniam, Vincenza Caruana,Kiran Makhani,Carolyn J. Baglole,Koren K. Mann
FRONTIERS IN TOXICOLOGY (2023): 1244596-1244596
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