Carl S Rye

Ctr Canc Drug Discovery Inst Canc Res, Div Canc Therapeut, London SW73RP, England

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论文共 18 篇作者统计合作学者相似作者

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HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen As a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies

A. Elisa Pasqua,Swee Y. Sharp,Nicola E. A. Chessum,Angela Hayes,Loredana Pellegrino,Michael J. Tucker,Asadh Miah,Birgit Wilding,Lindsay E. Evans,Carl S. Rye,N. Yi Mok,Manjuan Liu,Alan T. Henley,Sharon Gowan,Emmanuel De Billy,Robert te Poele,Marissa Powers,Suzanne A. Eccles,Paul A. Clarke,Florence I. Raynaud,Paul Workman,Keith Jones,Matthew D. Cheeseman

JOURNAL OF MEDICINAL CHEMISTRYno. 8 (2023): 5907-5936

引用1浏览0WOS引用

Privileged Structures and Polypharmacology Within and Between Protein Families

Joshua Meyers,Nicola E. A. Chessum,Salyha Ali,N. Yi Mok,Birgit Wilding,A. Elisa Pasqua,Martin Rowlands,Michael J. Tucker,Lindsay E. Evans,Carl S. Rye,Lisa O'Fee,Yann-Vai Le Bihan,Rosemary Burke,Michael Carter,Paul Workman,Julian Blagg,Nathan Brown,Rob L. M. van Montfort,Keith Jones,Matthew D. Cheeseman

ACS Medicinal Chemistry Letters（2018）

引用16浏览0WOS引用

Abstract LB-304: Discovery of Chemical Probe CCT251236: an Orally Bioavailable Efficacious Pirin Ligand from an HSF1 Phenotypic Screen

Matthew D. Cheeseman,Nicola E. Chessum,Carl S. Rye,Elisa A. Pasqua,Michael J. Tucker,Birgit Wilding,Lindsay E. Evans,Susan Lepri,Meirion Richards,Swee Y. Sharp,Salyha Ali,Martin Rowlands,Lisa O'Fee,Asadh Miah,Angela Hayes,Alan T. Henley,Marissa Powers,Robert te Poele,Emmanuel De Billy,Loredana Pellegrino,Florence Raynaud,Rosemary Burke, Robert L. van Montfort,Suzanne A. Eccles,Keith Jones,Paul Workman

Cancer Researchno. 13_Supplement (2017)

引用0浏览0引用

Discovery Of Chemical Probe Cct251236: An Orally Bioavailable Efficacious Pirin Ligand From An Hsf1 Phenotypic Screen

Matthew D. Cheeseman,Nicola E. A. Chessum,Carl S. Rye,Elisa Pasqua,Michael Tucker,Birgit Wilding,Lindsay E. Evans,Susan Lepri,Meirion Richards,Swee Y. Sharp,Salyha Ali,Martin G. Rowlands,Lisa O'Fee,Asadh Miah,Angela Hayes,Alan T. Henley,Marissa V. Powers,Robert te Poele,Emmanuel de Billy,Loredana Pellegrino,Florence I. Raynaud,Rosemary Burke,Rob L. M. van Montfort,Suzanne A. Eccles,Keith Jones,Paul Workman

CANCER RESEARCH（2017）

引用0浏览0引用

化学プローブ,ビスアミド(CCT251236)の発見:熱ショック転写因子1(HSF1)表現型スクリーニングからの経口吸収が可能な効果的なピリンリガンド

D Cheeseman Matthew,E A Chessum Nicola,Smythe Carl,Pasqua A. Elisa,J Tucker Michael,Birgit Wilding,E Evans Lindsay,L Mooberry Susan,Richards Meirion,Y Sharp Swee,Salyha Ali,Rowlands Martin,Lisa O’Fee,Asadh Miah,Hayes Angela,T Henley Alan,Powers Marissa,TE Poele Robert,DE Billy Emmanuel,Loredana Pellegrino,Raynaud Florence,Burke Rosemary,L M Van Montfort Rob,A Eccles Suzanne,W R Harris Paul,Jones Keith

Journal of medicinal chemistryno. 1 (2017): 201

引用0浏览0引用

Discovery Of Cct251236 From An Hsf1 Phenotypic Screen: A Pirin Ligand With Efficacy In An Ovarian Adenocarcinoma Model

Elisa Pasqua,Matthew Cheeseman,Nicola Chessum,Carl Rye,Michael Tucker,Birgit Wilding,Lindsay Evans,Susan Lepri,Meirion Richards,Swee Sharp,Salyha Ali,Martin Rowlands,Lisa O'Fee,Asadh Miah,Angela Hayes,Alan Henley,Marissa Powers,Robert Te Poele,Emmanuel De Billy,Loredana Pellegrino,Florence Raynaud,Rosemary Burke,Rob Van Montfort,Suzanne Eccles,Paul Workman,Keith Jones

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY (2017)

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Correction: Discovery of 4,6-Disubstituted Pyrimidines As Potent Inhibitors of the Heat Shock Factor 1 (HSF1) Stress Pathway and CDK9. See DOI: 10.1039/C6md00159a

Carl S. Rye,Nicola E. A. Chessum,Scott Lamont,Kurt G. Pike,Paul Faulder,Julie Demeritt,Paul Kemmitt,Julie Tucker,Lorenzo Zani,Matthew D. Cheeseman,Rosie Isaac,Louise Goodwin,Joanna Boros,Florence Raynaud,Angela Hayes,Alan T. Henley,Emmanuel de Billy,Christopher J. Lynch,Swee Y. Sharp,Robert te Poele,Lisa O’ Fee,Kevin M. Foote,Stephen Green,Paul Workman,Keith Jones

MedChemCommno. 9 (2016): 1870-1870

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Discovery of 4,6-Disubstituted Pyrimidines As Potent Inhibitors of the Heat Shock Factor 1 (hsf1) Stress Pathway and Cdk9 (vol 7, Pg 1580, 2016)

Carl S. Rye,Nicola E. A. Chessum,Scott Lamont,Kurt G. Pike,Paul Faulder,Julie Demeritt,Paul Kemmitt,Julie Tucker,Lorenzo Zani,Matthew D. Cheeseman,Rosie Isaac,Louise Goodwin,Joanna Boros,Florence Raynaud,Angela Hayes,Alan T. Henley,Emmanuel de Billy,Christopher J. Lynch,Swee Y. Sharp,Robert te Poele,Lisa O' Fee,Kevin M. Foote,Stephen Green,Paul Workman,Keith Jones

MEDCHEMCOMMno. 9 (2016): 1870-1870

引用0浏览0引用

Discovery of 4,6-Disubstituted Pyrimidines As Potent Inhibitors of the Heat Shock Factor 1 (HSF1) Stress Pathway and CDK9

Carl S. Rye,Nicola E. A. Chessum,Scott Lamont,Kurt G. Pike,Paul Faulder,Julie Demeritt,Paul Kemmitt,Julie Tucker,Lorenzo Zani,Matthew D. Cheeseman,Rosie Isaac,Louise Goodwin,Joanna Boros,Florence Raynaud,Angela Hayes,Alan T. Henley,Emmanuel de Billy,Christopher J. Lynch,Swee Y. Sharp,Robert Te Poele,Lisa O'Fee,Kevin M. Foote,Stephen Green,Paul Workman,Keith Jones

MedChemComm（2016）

引用17浏览0WOS引用

Discovery of a Chemical Probe Bisamide (CCT251236): an Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

Matthew D. Cheeseman,Nicola E. A. Chessum,Carl S. Rye,A. Elisa Pasqua,Michael J. Tucker,Birgit Wilding,Lindsay E. Evans,Susan Lepri,Meirion Richards,Swee Y. Sharp,Salyha Ali,Martin Rowlands,Lisa O'Fee,Asadh Miah,Angela Hayes,Alan T. Henley,Marissa Powers,Robert te Poele,Emmanuel De Billy,Loredana Pellegrino,Florence Raynaud,Rosemary Burke,Rob L. M. van Montfort,Suzanne A. Eccles,Paul Workman,Keith Jones

Journal of medicinal chemistry（2016）

引用41浏览0WOS引用

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作者统计

#Papers: 18

#Citation: 320

H-Index: 9

G-Index: 11

Sociability: 5

Diversity: 2

Activity: 0

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