C.E. Eapen - Christian Medical College Vellore

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Bio

Low volume plasma exchange and low dose steroid ("Vellore protocol") ameliorates macrophage activation and improves survival in patients with acute liver injury. Most of these patients have secondary hemophagocytic lymphohistiocytosis (sHLH). This treatment may help patients with severe COVID-19, acute lung injury and sHLH. Plasma von Willebrand factor levels (marker of endothelial activation) need to be studied. Clinical trials using this treatment are needed in COVID-19.

Research Interests

Papers共 274 篇Author StatisticsCo-AuthorSimilar Experts

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On-treatment Decline in MELD Score Predicts One-Month Transplant-Free Survival in Rodenticidal Hepatotoxicity Patients Treated with Low-Volume Plasma Exchange

Vijay Alexander, Gayathiri Kaduvetti Chellaiya, S. Gnanadeepam,Vinoi George David,Ebor James,Subramani Kandasamy,Kundavaram Paul Prabhakar Abhilash,Santosh Varughese,Sukesh Chandran Nair, Sandeep Kumar, P. Krishna Bharadwaj, S. Akilesh,Santhosh E. Kumar,Dolly Daniel, Sumathy Jayaraman,Uday Zachariah,Chundamannil E. Eapen,Ashish Goel

Indian Journal of Gastroenterologypp.1-8, (2024)

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Imbalance in the Vwf – ADAMTS13 Axis Exists Early in Acute Pancreatitis and Predicts Persistent Organ Failure and Pancreatic Necrosis-a Prospective Study

P.S. Sairam,Sudipta Dhar Chowdhury,Ajith Thomas,Anoop John,Rajeeb Jaleel,Reuben Thomas Kurien,Amit Kumar Dutta,Ebby George Simon,Tulasi Geevar,Sukesh Chandran Nair,Reka Karuppusami,C.E. Eapen, Joseph

Pancreatology official journal of the International Association of Pancreatology (IAP) et alno. 7 (2024): 986-992

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Single-Centre Experience with Low-Volume Plasma Exchange and Low-Dose Steroid to Treat Patients with Idiosyncratic Drug-Induced Acute Liver Failure

Kunwar A. Singh,Santhosh E. Kumar,Uday G. Zachariah,Dolly Daniel,Vinoi David,Kandasamy Subramani,Kishore Pichamuthu,Ebor Jacob,Thomas A. Kodiatte,Chundamannil E. Eapen,Ashish Goel

JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGYno. 2 (2024)

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THU-058 Portal Vein Thrombosis Increases Short-Term Mortality Independent of Liver Disease Severity Score among Hospitalized Patients of Decompensated Cirrhosis-Result from CLEARED Consortium

Ashok Choudhury, Xie Quan,Mark D. Topazian, Aldo Torre,Peter Hayes, Hailemichael Desalegn, Ramazan İdilman,Zhujun Cao,Mário Reis Álvares‐da‐Silva,Jacob George,Wai‐Kay Seto,Florence Wong,Patrick S. Kamath,Shiv Kumar Sarin,Brian Bush,Leroy R. Thacker, Anoop Saraya,Haydar Adanır,Busra Haktaniyan,Anand J. Kulkarni,Sezgin Barutçu,Sumeet K. Asrani,Hong Tang,Maria Sarai González-Huezo,Chundamannil E. Eapen,Kessarin Thanapirom,Jing Liu,Elizabeth C. Verna, M Rela, Alper Uysal,Jacqueline Córdova-Gallardo,Jose Antonio Velarde-Ruiz Velasco,Matheus Truccolo Michalczuk,Gustavo Pereira, Orlando M. Gutiérrez, Abraham Ramos Pineda,Abha Nagral, Dickinson Brian P,Dibya Lochan Praharaj,Rahmi Aslan,Paul J. Thuluvath,Hugo E. Vargas,Tolga Kosay,Beiling Li,Jie Li,Suresh Vasan Venkatachalapathy, Sunil Taneja, Stephen M. Riordan,Jawaid Shaw, Diana E. Yung,Adam Doyle,Yan Yue James Fung,Huan Deng,Lei Wang,Han Khim Tan, A E Hala,Amany Zekry,Liane Rabinowich, Meini Su, Xiaoping Wu, Xinrui Wang, Y Zhang,Caiyan Zhao,Zhiliang Gao,Feng Guo, Michael Schultheis,Puneeta Tandon,Bilal Bobat,K. Rajender Reddy,Ricardo Cabello Negrillo,Scott W. Biggins,Nipun Verma,Jasmohan S. Bajaj

Journal of hepatology (2024): S161-S162

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Focused Panel Sequencing Points to Genetic Predisposition in Non-Cirrhotic Intrahepatic Portal Hypertension Patients in India

Rekha Aaron, Kalpana Premkumar,Aaron Chapla,B. Vijayalekshmi,Uday Zachariah,Elwyn Elias,Thomas Alex Kodiatte,Dolly Daniel,John Jude,K. A. Balasubramanian,Sukesh C. Nair,Nihal Thomas,Banumathi Ramakrishna,C. E. Eapen,Ashish Goel

INDIAN JOURNAL OF GASTROENTEROLOGYno. 2 (2024): 434-442

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APASL Clinical Practice Guidelines on the Management of Acute Kidney Injury in Acute-on-chronic Liver Failure

Hepatology internationalno. 3 (2024): 833-869

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THU-052 Therapeutic Plasma-Exchange Improves Short-Term Survival in Patients with ACLF Admitted to Intensive Care Unit with Organ Failures-a Multinational AARC Data Analysis

Rakhi Maiwall,Samba Siva Rao Pasupuleti,Ashok Choudhury,Vinod Arora, M Rela,Dinesh Jothimani,Mamun Al‐Mahtab,Harshad Devarbhavi,Chundamannil E. Eapen,Ashish Goel,César Yaghi,Ning Qin,Tao Chen,Jidong Jia,Zhongping Duan, Hamid Salehiniya,Amna Subhan, Wasim Jafri, Akash Shukla,Soek-Siam Tan,Dong Joon Kim, Anoop Saraya,Jinhua Hu,Ajit Sood,Omesh Goyal,Vandana Midha,Manoj Kumar Sahoo,Guan Huei Lee,Sombat Treeprasertsuk,Kessarin Thanapirom,Ameet Mandot, Samir Shah,Laurentius A. Lesmana,Hasmik Ghazinyan, Mario Calvo G,A. Kadir Dokmeci,Jose D. Sollano,Zaigham Abbas,Ananta Shrestha,George Lau,Diana Payawal,Gamal Shiha,Ajay Duseja, Sunil Taneja,Nipun Verma, Nagaraja Rao Padaki, Anand V. Kulkarni,Mithun Sharma,Md. Fazal Karim,Radha K. Dhiman,Ajay Kumar Mishra,Shahinul Alam,Osamu Yokosuka,Debashis Chowdhury,Chandan Kedarisetty,Sanjiv Saigal,Anil Arora, Alka Kumar,Abraham Koshy,Ajay Kumar,Mohamed Elbasiony,Pravin Rathi,Sudhir Maharshi,Vishwa Mohan Dayal,Ashish Kumar Jha,Kemal Fariz Kalista, Rino Alvani Gani,Man Fung Yuen,Virendra Singh,Ayaskanta Singh, Sargsyan Violeta, Ching‐Wen Huang,Saurabh Mukewar,Shaojie Xin,Ruveena Bhavani,Charles Panackel,Sunil Dadhich,Sanjeev Sachdeva,Sanatan Behera,Prabir Maji,Lubna Kamani, Hemamala Venugopal Saithanyamurthi,Joy Varghese,Pathik Parikh, P Javed,Neeraj Saraf,Narendra S. Choudhary,Akash Roy,Mahesh K. Goenka,Chetan Kalal, Krishnadas Devadas, J H,Shiv Kumar Sarin

Journal of hepatology (2024): S158-S159

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Plasma exchange improves survival in acute liver failure - An updated systematic review and meta-analysis focussed on comparing within single etiology

Kausala Sithamparapillai,Uday Zachariah,C. E. Eapen,Ashish Goel

Indian Journal of Gastroenterologyno. 2 (2024): 1-10

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Extra-corporeal Non-Liver Transplant Therapies for Acute Liver Failure: Focus on Plasma Exchange and Continuous Renal Replacement Therapy

Uday Zachariah,Balakrishnan Vijayalekshmi, Smita M. Matthai,Ashish Goel,Chundamannil E. Eapen

Indian Journal of Gastroenterology（2024）

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