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My research has concentrated on finding out the reason why patients in advanced stages of cirrhosis develop complications. It is a stage of the disease called decompensated cirrhosis, when patients are at risk for developing trouble in other organ systems, and then their condition suddenly deteriorates. This scenario is known as acute-on-chronic liver failure, where there is a risk for kidney, brain and lung failure. So far, we know that bacterial infections are a major cause of acute-on-chronic liver failure, but there are other situations when there is inflammation without infection can also cause multi-organ failure. I have spent some time investigating kidney failure associated with liver failure. This is related to both a change in the circulation in these patients as well as the presence of inflammation. I have been studying the role of a group of compounds called vasoconstrictors to manipulate the circulation. These have helped to improve kidney function in these patients, suggesting that abnormalities in the circulation can cause kidney failure to occur in patients with cirrhosis. I have also been involved in studies to find out how changes of the bacteria in patients' guts can cause complications of cirrhosis. We are in the process of designing further studies to manipulate gut bacteria to reduce the risk for these patients to develop complications.
研究兴趣
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Ashok Choudhury, Xie Quan,Mark D. Topazian, Aldo Torre,Peter Hayes, Hailemichael Desalegn, Ramazan İdilman,Zhujun Cao,Mário Reis Álvares‐da‐Silva,Jacob George,Wai‐Kay Seto,Florence Wong,Patrick S. Kamath,Shiv Kumar Sarin,Brian Bush,Leroy R. Thacker, Anoop Saraya,Haydar Adanır,Busra Haktaniyan,Anand J. Kulkarni,Sezgin Barutçu,Sumeet K. Asrani,Hong Tang,Maria Sarai González-Huezo,Chundamannil E. Eapen,Kessarin Thanapirom,Jing Liu,Elizabeth C. Verna, M Rela, Alper Uysal,Jacqueline Córdova-Gallardo,Jose Antonio Velarde-Ruiz Velasco,Matheus Truccolo Michalczuk,Gustavo Pereira, Orlando M. Gutiérrez, Abraham Ramos Pineda,Abha Nagral, Dickinson Brian P,Dibya Lochan Praharaj,Rahmi Aslan,Paul J. Thuluvath,Hugo E. Vargas,Tolga Kosay,Beiling Li,Jie Li,Suresh Vasan Venkatachalapathy, Sunil Taneja, Stephen M. Riordan,Jawaid Shaw, Diana E. Yung,Adam Doyle,Yan Yue James Fung,Huan Deng,Lei Wang,Han Khim Tan, A E Hala,Amany Zekry,Liane Rabinowich, Meini Su, Xiaoping Wu, Xinrui Wang, Y Zhang,Caiyan Zhao,Zhiliang Gao,Feng Guo, Michael Schultheis,Puneeta Tandon,Bilal Bobat,K. Rajender Reddy,Ricardo Cabello Negrillo,Scott W. Biggins,Nipun Verma,Jasmohan S. Bajaj
Journal of hepatology (2024): S161-S162
Wai-Kay Seto,Qing Xie,Ashok Kumar Choudhury,Patrick S. Kamath,Mark Topazian,Peter Hayes, Aldo Torre, Hailemichael Desalegn, Ramazan Idilman,Zhujun Cao,Mario Álvares-da-Silva,Jacob George,Florence Wong,Brian Bush,Leroy Thacker,Shiv Kumar Sarin,Iliana Mani,Dinc Dincer, Diederick van Doorn,Amey Sonavane,Mohammad Amin Fallahzadeh, Linlin Wei,Araceli Bravo Cabrera,Ashish Goel, Ponan, Shiva Kumar, Yu Jun Wong,Dinesh Jothimani,Matthew Robert Kappus,Abdullah Emre Yıldırım, Ewan H Forrest,Francisco Félix Tellez,Patricia Momoyo Zitelli,Manuel Barbero,José Luis Pérez-Hernández,Sebastián Marciano,René Malé Velazquez,Ajay Jhaveri,Robert Gibson,Anil Chandra Anand,Tahrima Kayes,Feyza Gunduz,David Bayne,Minghua Lin,Enver Ucbilek,Nabil Debzi, Jian Wang,Yashwi Haresh Kumar Patwa,Ajay Kumar Duseja,Marco Arrese,Rosemary Faulkes, James Kennedy, Yu Sung Kim,Radha Krishan Dhiman,Hai Li,Dedong Yin, Yanyun Zhang,Gerry MacQuillan,Ashish Kumar,Helena Katchman,Yingling Wang,Qunfang Rao,Yijing Cai, Liyang Wu,Yongfang Jiang, Zhen Xu,Yongchao Xian,Dominik Bettinger,Monica Dahiya,Nabiha Faisal,Duarte Rojo Andres,Natalia Filipek,Fiona Tudehope, Wanqin Zhang,Jasmohan Bajaj
Journal of Hepatology (2024)
Sebastian Marciano,Salvatore Piano,Virendra Singh,Paolo Caraceni,Rakhi Maiwall,Carlo Alessandria, Javier Fernandez,Dong Joon Kim,Sung Eun Kim, Elza Soares,Monica Marino,Julio Vorobioff,Manuela Merli,Laure Elkrief,Victor Vargas,Aleksander Krag,Shivaram Singh,Martin Elizondo,Maria M. Anders,Melisa Dirchwolf,Manuel Mendizabal,Cosmas R. A. Lesmana,Claudio Toledo,Florence Wong,Francois Durand,Adrian Gadano,Diego H. Giunta,Paolo Angeli
Liver international official journal of the International Association for the Study of the Liverno. 11 (2024): 2915-2928
CURRENT OPINION IN GASTROENTEROLOGYno. 3 (2024): 156-163
Jasmohan S. Bajaj, Ashok Choudhury,Vinay Kumaran,Florence Wong,Wai Kay Seto,Mario Reis Alvares-Da-Silva, Hailemichael Desalgn,Peter C. Hayes, Ramazan Idilman,Mark Topazian, Aldo Torre,Qing Xie,Jacob George,Patrick S. Kamath
American Journal of Transplantation (2024)
ACG CASE REPORTS JOURNALno. 6 (2024)
Rakhi Maiwall,Salvatore Piano,Virendra Singh,Paolo Caraceni,Carlo Alessandria,Javier Fernandez,Elza Cotrim Soares,Dong Joon Kim, Sung Eun Kim,Monica Marino,Julio Vorobioff,Rita de Cassia Ribeiro Barea,Manuela Merli,Laure Elkrief, Victor Vargas,Aleksander Krag,Shivaram Prasad Singh,Laurentius Adrianto Lesmana,Claudio Toledo,Sebastian Marciano,Xavier Verhelst,Florence Wong,Nicolas Intagliata,Liane Rabinowich,Luis Colombato, Sang Gyune Kim,Alexander Gerbes,Francois Durand,Juan Pablo Roblero, Kalyan Ram Bhamidimarri, Marina Maevskaya,Eduardo Fassio, Hyoung Su Kim, Jae Seok Hwang,Pere Gines, Tony Bruns,Adrian Gadano,Paolo Angeli,Shiv Kumar Sarin
Gastroenterologyno. 5 (2024): S-1588-S-1589
LIVER TRANSPLANTATIONno. 4 (2024): 347-355
ALIMENTARY PHARMACOLOGY & THERAPEUTICSno. 10 (2024): 1196-1211
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作者统计
#Papers: 513
#Citation: 17801
H-Index: 68
G-Index: 127
Sociability: 7
Diversity: 3
Activity: 102
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