His own research group studies the immunological basis of asthma and respiratory viral infections, and he has published some 400 articles and book chapters on this topic. He received numerous prizes, including the Pharmacia Allergy Research Foundation Prize (2008), Franqui Prize (2014), the ERS Asthma Gold Medal (2016) and the FWO Excellence Prize Fundamental Biomedical Sciences (2020). In 2020 he coördinated 3 clinical trials on the use of immunomodulatory drugs in the treatment of COVID-19, in total enrolling more than 500 patients. His current work for which he received an ERC Advanced Grant involves the role of protein crystals in type 2 immunity in asthma and chronic rhinosinusitis.