His research interests include: super-resolution and 3D optical microscopy, digital holographic microscopy, optical micro-manipulation and micro-fabrication, optical data storage and information processing. He invented the DMD-based LED-illumination structured illumination microscope (D-SIM) and got the 90nm lateral resolution. He designed and developed an optical tweezers system, which has been successfully commercialized and exported to Canada. He proposed a new theoretical description for the vector beams, and predicted the improvement of axial trapping efficiency by radially polarized beams. He proposed a new approach to generation of multiple isotropic super-diffraction-limit focused spots and the dynamic shifting method. He implemented the high density holographic optical encoded data storage in biomaterial. He has published more than 230 papers in peer-reviewed journals and 6 book’s chapters, and owned 18 China & 1 US invention patents. He obtained the “High-speed Imaging Award of Japan” in 2015.