Astrid Valles-Sanchez - UniQure | 人才画像

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论文共 55 篇作者统计合作学者相似作者

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Exon 1-targeting miRNA reduces the pathogenic exon 1 HTT protein in Huntington disease models

Marina Sogorb-Gonzalez,Christian Landles,Nicholas S Caron,Anouk Stam,Georgina Osborne,Michael R Hayden,David Howland,Sander van Deventer,Gillian P Bates,Astrid Vallès,Melvin Evers

Brain : a journal of neurology (2024)

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Proof-of-concept Study for Liver-Directed Miqure Technology in a Dyslipidemic Mouse Model

Vanessa Zancanella,Astrid Vallès,Jolanda M.P. Liefhebber,Lieke Paerels, Carlos Vendrell Tornero,Hendrina Wattimury,Tom van der Zon,Kristel van Rooijen,Monika Golinska, Tamar Grevelink,Erich Ehlert,Elsbet J. Pieterman,Nanda Keijzer,Hans Marinus Gerardus Princen,Geurt Stokman,Ying Poi Liu

Molecular therapy Nucleic acidsno. 2 (2024): 102189-102189

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LinQURE: A Novel AAV Gene Silencing Platform That Supports Multi-Transcript Targeting for Complex Disorders

Irena Boc, Anna Moreno Garcia, Pablo de Miguel Herraiz,Sonay Keskin,Vanessa Zancanella, Seyda Acar Broekmans,Astrid Valles,Ying Poi Liu,Melvin Evers,Morgane Wartel

MOLECULAR THERAPY NUCLEIC ACIDSno. 3 (2024)

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A006 Splicing Dysregulation is a Common Theme Across Huntington’s Disease Mouse Models and Can Be Rescued by Huntingtin Lowering

Leontien van der Bent,Melvin Evers,Astrid Valles

A Pathogenic mechanisms (2024)

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Proof-of-concept Study for Liver-Directed Miqure Technology in a Dyslipidemic Mouse Model

Vanessa Zancanella,Astrid Valles,Jolanda M. P. Liefhebber,Lieke Paerels, Carlos Vendrell Tornero,Hendrina Wattimury,Tom van der Zon,Kristel van Rooijen,Monika Golinska, Tamar Grevelink,Erich Ehlert,Elsbet Jantine Pieterman,Nanda Keijzer,Hans Marinus Gerardus Princen,Geurt Stokman,Ying Poi Liu

Molecular Therapy - Nucleic Acids (2023): 454-467

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Combining Vectorized Antibody and miRNA Lowering Strategies for Synucleinopathies

Seya Acar-Broekmans, Rhode Erbrink,Nikki Timmer, Charlot Van Rooijen, Sebastian Kieper, Verena Hehle,Astrid Valles

MOLECULAR THERAPYno. 4 (2023): 708-708

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Development of an alpha-Synuclein Targeting Vectorized Antibody Strategy: First In Vivo Proof of Mechanism in Wild Type Mice

Seya Acar-Broekmans, Rhode Erbrink, Charlot Van Rooijen,Lukas K. Schwarz, Meriem Bourajjaj, Laura Tade, Verena Hehle,Astrid Valles

MOLECULAR THERAPYno. 4 (2023): 494-494

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Alpha-Synuclein Lowering and Rescue of Motor Phenotype by miRNA-Based AAV Gene Therapy in In Vivo Parkinson's Disease Models

Seyda Acar Broekmans, Carlos Vendrell Tornero,Lodewijk Toonen,Mercedes Valls, Rhode Erbrink, Kaila E. Ronde,Wytse Hogewerf, Lisette E. D. Tolsma,Renee I. Seinstra,Leen L. S. Janssen,Ellen A. A. Nollen,Astrid Valles

MOLECULAR THERAPY（2022）

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Emerging Therapies for Huntington’s Disease – Focus on N-Terminal Huntingtin and Huntingtin Exon 1

M. Leontien van der Bent,Melvin M. Evers,Astrid Valles

DOAJ (DOAJ Directory of Open Access Journals)（2022）

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Functional Intercellular Transmission of Mihtt Via Extracellular Vesicles: an in Vitro Proof-of-Mechanism Study

Roberto D. V. S. Morais,Marina Sogorb-Gonzalez,Citlali Bar,Nikki C. Timmer,M. Leontien Van der Bent,Morgane Wartel,Astrid Valles

Cells（2022）

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