Her research interests lie in the areas of computational biology, gene expression and regulation analyses and machine learning. She has published in top tier journals as Nature, Science, Proceedings of the National Academy of Sciences of the United States of America, American Journal of Human Genetics, Genes and Development, Nature Methods and Genome Research. Her works have been cited more than 18,000 times (h-index 49) according to Google Scholar (2020). She has served as a reviewer panelist for the Welcome Trust Sanger Institute (UK), the National Science Foundation (NSF-USA), the National Institute of Health (NIH-USA), the European Union (FP7, CONNECT) and the Greek Secretary of Research and Technology. She is currently President of the Hellenic Society for Computational Biology and Bioinformatics (HSCBB) and she was the chair of the 17th European Conference on Computational Biology (ECCB18).