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个人简介
Dr. Chapman's research focuses on clinical manifestations of autosomal dominant polycystic kidney disease (ADPKD). Dr. Chapman has been heavily involved in the development of novel imaging biomarkers for this disease using magnetic resonance imaging and calculating total kidney volume (TKV). Clinical trials testing appropriate levels of blood pressure control, inhibition of the vasopressin V2 receptor, epidermal growth factor receptor inhibition and alterations in fluid intake and dietary amino acids and their impact on disease progression are currently active.. Dr. Chapman also studies personalized or precision medicine and the role that genetic background plays in predicting antihypertensive responses to blood pressure medications used to treat hypertension as well as disease progression in ADPKD. Dr. Chapman's early investigations centered on demonstrating that the renal and systemic changes that occur during pregnancy happen early, by the sixth week of pregnancy. She has received continuous funding for her work from the National Institutes of Health (NIH) over the past 20 years.
研究兴趣
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Medical Imaging 2024: Computer-Aided Diagnosis (2024)
Journal of the American Heart Associationno. 4 (2024): e032433-e032433
Brandon Elliott, Karla M Márquez-Nogueras, Paula Thuo,Elisabeth DiNello, Ryne M Knutila, Geena E Fritzmann,Monte Willis,Arlene B Chapman,Quan Cao,David Y Barefield,Ivana Y Kuo
bioRxiv : the preprint server for biology (2024)
Clinical and translational scienceno. 5 (2024): e13816-e13816
Mina Al Sayyab,Arlene Chapman
Advances in kidney disease and healthno. 5 (2023): 454-460
Victoria C. Gauntner, Ghaleb H. Daouk, Melanie P. Napier,Martine T. Besouw, Christopher J. LaRosa,Alanna Strong,Shrikant M. Mane,Shirlee Shril,Arlene B. Chapman,Friedhelm Hildebrandt,John A. Sayer,Amar J. Majmundar
Journal of the American Society of Nephrologyno. 11S (2023): 938-938
Rosanna Cazzolli,Angela Ju,Patrizia Natale, Eva Burnette,Niek F. Casteleijn,Arlene Chapman, Sarah Eastty,Ron T. Gansevoort,Tess Harris,Marie Hogan,Shigeo Horie,Bertrand Knebelmann,
NEPHROLOGY (2023): 39-39
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Kidney Internationalno. 2 (2023): 334-342
Kidney360no. 4 (2023): 499-500
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