Van der Ploeg has been/is a reviewer on several scientific boards, serves as advisor, and collaborates closely with national and international patient associations among which the International Pompe patient Association (IPA). She serves as ad hoc reviewer for various scientific journals. She is member of the World Muscle Society and Study Group of Inborn Errors of Metabolism (SSIEM). She has been organizer of several international meetings among which 12 international Pompe expert days; the MPS Symposium in 2012 with 750 participants. She will be organizer of the SSIEM symposium in 2019 with over 2000 participants. She participates in 7th EU Framework Programme ‘Euclyd – a European Consortium for Lysosomal Storage Diseases’ [health F2/2008 grant agreement 201678] and European Community’s Seventh Framework Programme (FP7/2007-2013) – MeuSIX [304999] –(Gene therapy for MPS VI).