Anne-Laure Blayo - Department of Molecular Therapeutics, The Scripps Research Institute

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论文共 32 篇作者统计合作学者相似作者

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Abstract 684: DT-9045, a Novel PAR2 Inhibitor with Best-in-class Properties That Reduces Resistance to Both EGFR-targeting Therapies and Immunotherapy in Oncology Models

Thibaut Brugat, Maleck Kadiri, Samya Aouad,Anne-Laure Blayo, Baptiste Rugeri, Antoine Mousson, Aurélie Janvier,Edith Steinberg,Luc Baron, Mandy Recolet, Xavier Wirth, Maria Jesus Garcia-Leon,Quentin Ruet,Meriem Semache,Laurent Sabbagh,Orphée Blanchard,Christel Franchet,Stanislas Mayer,John Stagg,Nathalie Lenne,Stephan Schann

Cancer Researchno. 6_Supplement (2024): 684-684

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Abstract 4961: Novel Biased PAR2 Inhibitors with Best-in-class Properties Reduce Resistance to Both Chemotherapy and Immunotherapy in Oncology Models

Thibaut Brugat,Francesco Bergami, Baptiste Rugeri, Aurélie Janvier,Edith Steinberg,Luc Baron, Mandy Recolet, Xavier Wirth,Meriem Semache, Antoine Mousson,Camille Dietsch,Quentin Ruet,Orphée Blanchard,Célia Jacoberger-Foissac,Isabelle Cousineau, Maleck Kadiri,Anne-Laure Blayo,Christel Franchet,Stanislas Mayer,John Stagg,Nathalie Lenne,Stephan Schann

Cancer Researchno. 7_Supplement (2023): 4961-4961

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PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles

Rebecca L. Frkic,Jordan L. Pederick,Aimee J. Horsfall,Blagojce Jovcevski,Elise E. Crame,Wioleta Kowalczyk,Tara L. Pukala,Mi Ra Chang,Jie Zheng,Anne-Laure Blayo,Andrew D. Abell,Theodore M. Kamenecka,Joshua S. Harbort,Jeffrey R. Harmer,Patrick R. Griffin,John B. Bruning

ACS CHEMICAL BIOLOGYno. 5 (2023): 1115-1123

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814 DT-9081, a Selective EP4receptor Antagonist Which Synergizes with Immune Checkpoint Inhibitors to Induce Complete Responses in Syngeneic Murine Cancer Models

Anne-Laure Blayo,Claire Jouffroy-Zeller,Nathalie Lenne,Imane Nafia, Patricia Zerr,Stephan Schann,Xavier Leroy

Regular and Young Investigator Award Abstracts (2022)

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Abstract 934: “Gpcr-Ome” Modulation Upon PD1 / PDL1 Axis Blockade

Imane Nafia,Xavier Leroy,Loic Cerf,Jean-Philippe Guegan,Anne-Laure Blayo,Antoine Italiano,Stephan Schann,Alban Bessede

Cancer research（2020）

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817 DT095895, a Selective EP4 Receptor Antagonist with Monotherapy Efficacy in Syngeneic Mouse Model(s) and Best-in-class Properties

Anne-Laure Blayo,Laurene Deshons, Alexia Dumont,Christel Franchet,Celia Halter, Ludovic Herbin, Gael Hommet,Stanislas Mayer,Alban Bessede,Imane Nafia,Marjorie Sidhoum,Xavier Leroy,Stephan Schann

Cancer research（2020）

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Definition of Functionally and Structurally Distinct Repressive States in the Nuclear Receptor PPARγ

Zahra Heidari,Ian M. Chrisman,Michelle D. Nemetchek,Scott J. Novick,Anne-Laure Blayo, Trey Patton, Desiree E. Mendes,Philippe Diaz,Theodore M. Kamenecka,Patrick R. Griffin,Travis S. Hughes

Nature Communications（2019）

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A Structural Mechanism for Directing Corepressor-Selective Inverse Agonism of PPARγ

Richard Brust,Jinsai Shang,Jakob Fuhrmann,Sarah A. Mosure,Jared Bass,Andrew Cano,Zahra Heidari,Ian M. Chrisman,Michelle D. Nemetchek,Anne-Laure Blayo,Patrick R. Griffin,Theodore M. Kamenecka,Travis S. Hughes,Douglas J. Kojetin

Nature communications（2018）

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Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism

Jie Zheng,Cesar Corzo,Mi Ra Chang,Jinsai Shang,Vinh Q Lam,Richard Brust,Anne-Laure Blayo,John B Bruning,Theodore M Kamenecka,Douglas J Kojetin,Patrick R Griffin

Structure (London, England : 1993)（2018）

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