Andre da Silva Santiago - Centro de Biotecnologia e Genética, Universidade Estadual de Santa Cruz

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Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1Δ/ε

JOURNAL OF MEDICINAL CHEMISTRYno. 11 (2024): 8609-8629

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Discovery of Pyrazolo[3,4-D]pyrimidines As Novel Mitogen-Activated Protein Kinase Kinase 3 (MKK3) Inhibitors

Jessica E. Takarada,Micael R. Cunha,Vitor M. Almeida,Stanley N. S. Vasconcelos,Andre S. Santiago,Paulo H. Godoi,Anita Salmazo,Priscila Z. Ramos,Angela M. Fala,Lucas R. De Souza,Italo E. P. Da Silva,Mario H. Bengtson,Katlin B. Massirer,Rafael M. Counago

BIOORGANIC & MEDICINAL CHEMISTRY (2024)

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Molecular Basis of Β-Lactam Antibiotic Resistance of ESKAPE Bacterium E. Faecium Penicillin Binding Protein PBP5

Yamanappa Hunashal,Ganesan Senthil Kumar,Meng S. Choy,Éverton D. D’Andréa,Andre Da Silva Santiago,Marta V. Schoenle,Charlene Desbonnet,Michel Arthur,Louis B. Rice,Rebecca Page,Wolfgang Peti

Nature communicationsno. 1 (2023)

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Discovery of Novel Benzothiophene Derivatives As Potent and Narrow Spectrum Inhibitors of DYRK1A and DYRK1B

Natanael D. Segretti,Jessica E. Takarada,Marcos A. Ferreira,Andre da Silva Santiago,Bruno V. M. Teodoro, Mariana C. F. C. B. Damiao,Paulo H. Godoi,Micael R. Cunha,Angela M. Fala,Priscila Z. Ramos,Eloisa E. Ishikawa,Alessandra Mascarello,Ricardo A. M. Serafim,Hatylas Azevedo,Cristiano R. W. Guimaraes,Rafael M. Counago

Bioorganic & medicinal chemistry letters（2022）

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Structure of Human MPS1 (TTK) covalently bound to RMS-07 inhibitor

A.S. Santiago,C.V. dos Reis, R.A.M. Serafim,K.B. Massirer,P. Arruda, A.M. Edwards,R.M. Counago

crossref（2022）

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Development of the First Covalent Monopolar Spindle Kinase 1 (MPS1/TTK) Inhibitor

Ricardo A. M. Serafim,Andre da Silva Santiago,Martin P. Schwalm,Zexi Hu,Caio dos Reis,Jessica E. Takarada,Priscila Mezzomo,Katlin B. Massirer,Mark Kudolo,Stefan Gerstenecker,Apirat Chaikuad,Lars Zender,Stefan Knapp,Stefan Laufer,Rafael M. Counago,Matthias Gehringer

Journal of Medicinal Chemistry（2021）

引用9浏览0WOS引用

Structural Features and Development of an Assay Platform of the Parasite Target Deoxyhypusine Synthase of Brugia Malayi and Leishmania Major

Suelen Fernandes Silva,Angelica Hollunder Klippel,Priscila Zonzini Ramos,Andree da Silva Santiago,Sandro Roberto Valentini,Mario Henrique Bengtson,Katlin Brauer Massirer,Elizabeth Bilsland,Rafael Miguez Counago,Cleslei Fernando Zanelli

PLoS neglected tropical diseases（2020）

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Crystal Structure of Brugia malayi Deoxyhypusine synthase (DHPS)

A.S. Santiago,C.V. dos Reis,P.Z. Ramos, H.A. Klippel, S.F. Silva, C.F. Zanelli,K.B. Massirer,P. Arruda, A.M. Edwards,R.M. Counago,

crossref（2020）

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In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds

Sean N. O'Byrne,John W. Scott, Joseph R. Pilotte,Andre da S. Santiago,Christopher G. Langendorf, Jonathan S. Oakhill,Benjamin J. Eduful,Rafael M. Counago,Carrow I. Wells,William J. Zuercher,Timothy M. Willson,David H. Drewry

MOLECULES（2020）

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In Depth Analysis of Kinase Cross Screening Data to Identify CAMKK2 Inhibitory Scaffolds

Sean N. O’Byrne,John W. Scott, Joseph R. Pilotte,André de S. Santiago,Christopher G. Langendorf, Jonathan S. Oakhill,Benjamin J. Eduful,Rafael M. Couñago,Carrow I. Wells,William J. Zuercher, Timothy M. Willson,David H. Drewry

crossref（2020）

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