What we are working on: 1. Neuroinflammation of pre-autonomic nuclei that modulate adipose tissue activity in obese mice. 2. Effect of chronic systemic inflammation on neuroinflammation and its contribution to predisposition to damage by MPTP neurotoxin. 3. Modulation of the pathogenesis of Parkinson's disease with silybin coupled to nanoparticles. 4. Evaluation of the effect of photothermal therapy in an in vitro model of astrocytoma. 5. Study on the effect of silymarin on signaling pathways activated by endoplasmic reticulum stress in obese subjects.