The main thrust of my research is the development of novel treatment avenues for haematological disorders and cancer using gene transfer technology. I am in addition interested in stem cell biology
Recently we have begun a program of research on the use of induced pluripotent stem (iPS) cells for the treatment of degenerative conditions as well as disease models. Through funding from the UKRMP/MRC we evaluating methods for the generation of iPS cells in a GMP environment. In addition, through EU framework support we are assessing the potential of iPS cells as a source of cells for the treatment of malignancies and or organ failure.
Gene therapy for haematological malignancies: My haemato-oncology research is focused on the development of two emerging strategies: immunotherapy and anti-angiogenesis. Gene-therapy approaches are central to each of these strategies.