Chan Y Alina - Harvard University, MIT

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论文共 26 篇作者统计合作学者相似作者

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An AAV Capsid Reprogrammed to Bind Human Transferrin Receptor Mediates Brain-Wide Gene Delivery

Qin Huang,Ken Y. Chan,Jason Wu, Nuria R. Botticello-Romero,Qingxia Zheng, Shan Lou,Casey Keyes, Alexander Svanbergsson,Jencilin Johnston,Allan Mills, Chin-Yen Lin,Pamela P. Brauer,Gabrielle Clouse,Simon Pacouret, John W. Harvey,Thomas Beddow, Jenna K. Hurley,Isabelle G. Tobey,Megan Powell,Albert T. Chen,Andrew J. Barry,Fatma-Elzahraa Eid,Yujia A. Chan,Benjamin E. Deverman

SCIENCEno. 6701 (2024): 1220-1227

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Systematic Multi-Trait AAV Capsid Engineering for Efficient Gene Delivery

Fatma-Elzahraa Eid,Albert T. Chen,Ken Y. Chan,Qin Huang,Qingxia Zheng,Isabelle G. Tobey,Simon Pacouret,Pamela P. Brauer,Casey Keyes,Megan Powell,Jencilin Johnston,Binhui Zhao,Kasper Lage,Alice F. Tarantal,Yujia A. Chan,Benjamin E. Deverman

NATURE COMMUNICATIONSno. 1 (2024)

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Human CA4-Targeting AAV Capsids Efficiently Transduce the CNS in Humanized Mice

Nuria Roxana Botticello-Romero,Jason Wu, Qin Huang, Thomas Beddow, Ken Y. Chan, Pamela Brauer, Fatma Elzahraa Eid,Alina Chan, Benjamin E. Deverman

MOLECULAR THERAPYno. 4 (2024): 482-482

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Development of Stabilized AAV Capsids for Vector Engineering

Simon Pacouret,Fatma Elzahraa Eid, William Donahoe,Ken Y. Chan,Jason Wu,Qingxia Zheng,Casey Keyes,Pamela Brauer,Albert Chen,Yujia A. Chan,Benjamin Deverman

MOLECULAR THERAPYno. 4 (2023): 24-24

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Developing Blood-Brain Barrier-Crossing AAV9 Variants with Reduced Sensitivity to Neutralizing Antibodies

Simon Pacouret,Ken Y. Chan,Fatma Elzahraa Eid, William Donahoe,Pamela Brauer,Binhui Zhao,Qin Huang, Jencilin Johnson,Qingxia Zheng,Albert Chen,Andrew J. Barry,Casey Keyes,Yujia A. Chan,Benjamin E. Deverman

MOLECULAR THERAPYno. 4 (2023): 57-57

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Targeting AAV Vectors to the Central Nervous System by Engineering Capsid-Receptor Interactions That Enable Crossing of the Blood-Brain Barrier

Qin Huang, Albert T. J. Chen,Ken Y. Chan,Hikari Sorensen,Andrew Barry,Bahar Azari,Qingxia G. Zheng,Thomas Beddow,Binhui Zhao,Isabelle J. Tobey, Cynthia Moncada-Reid,Fatma-Elzahraa R. Eid, Christopher D. Walkey,M. Cecilia A. Ljungberg, William E. Lagor,Jason Heaney,Yujia Chan,Benjamin Deverman

PLOS BIOLOGY（2023）

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AAV-Mediated CNS-Wide Gene Delivery via a De Novo Engineered Capsid-Human Receptor Interaction

Ken Y. Chan,Qin Huang,Jencilin Johnston,Andrew J. Barry,Qingxia Zheng,Albert T. Chen,Thomas Beddow,Casey Keyes,Simon Pacouret,Pamela P. Brauer, Shan Lou,Gabrielle Clouse,Jason Wu, Nuria R. R. Navarrete,Fatma Elzahraa Eid,Yujia A. Chan,Benjamin E. Deverman

MOLECULAR THERAPYno. 4 (2023): 56-56

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The Machine Learning-Guided Fit4Function Platform Quantitatively Profiles the Biodistribution of Peptide-Modified AAV Capsids after a Single Round of Screening in Macaque

Fatma Elzahraa Eid,Albert Chen,Ken Chan,Qin Huang,Qingxia Zheng,Isabelle Tobey,Simon Pacouret,Pamela Brauer,Casey Keyes,Megan Powell,Jencilin Johnston,Binhui Zhao,Alice Tarantal,Yujia A. Chan,Benjamin Deverman

MOLECULAR THERAPYno. 4 (2023): 42-43

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Targeting AAV Vectors to the CNS Via De Novo Engineered Capsid-Receptor Interactions

Qin Huang,Albert T. Chen,Ken Y. Chan,Hikari Sorensen, Andrew Barry,Bahar Azari,Qingxia Zheng,Thomas Beddow,Binhui Zhao,Isabelle G. Tobey, Cynthia Moncada-Reid,Fatma-Elzahraa Eid,Christopher J. Walkey,M. Cecilia Ljungberg,William R. Lagor,Jason D. Heaney,Yujia A. Chan,Benjamin E. Deverman

Zenodo (CERN European Organization for Nuclear Research) (2023)

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A High-Efficiency AAV for Endothelial Cell Transduction Throughout the Central Nervous System

Trevor Krolak,Ken Y. Chan,Luke Kaplan,Qin Huang,Jason Wu,Qingxia Zheng,Velina Kozareva,Thomas Beddow,Isabelle G. Tobey,Simon Pacouret,Albert T. Chen,Yujia A. Chan, Daniel Ryvkin,Chenghua Gu,Benjamin E. Deverman

Nature cardiovascular research（2022）

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