Dr. Yu’s research interests include drug metabolism, pharmacokinetics, pharmacodynamics, noncoding RNAs, anticancer pharmacology and experimental therapeutics. The ultimate goal of his research is to translate noncoding RNAs to new therapies. Current efforts in his laboratory are directed to the investigation of (a) the mechanistic actions of microRNAs in the regulation of cellular processes including drug/xenobiotic/nutrient metabolism and disposition as well as tumor progression and metastasis, (b) novel RNA bioengineering technologies, and (c) recombinant RNAs for basic research and drug development.