My major research interest is clinical research in critically ill patients. Thus I currently chair the Scandinavian Critical Care Trials Group and the strategic research programme ‘New resuscitation strategies in patients with severe sepsis’. The program is ongoing and will randomize 2000 patients with severe sepsis in 3 RCTs of resuscitation in 25 ICUs in all the Nordic countries. The first RCT, the 6S trial has been published and the second, the TRISS trial, is ongoing and on track.