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职业迁徙
个人简介
I am a clinician scientist with a specialist interest in haemopoietic stem cell transplantation, genome editing, genomics and bioinformatics. I studied medicine at Oxford University before going on to complete specialist training in haematology and intensive care medicine in London. At present I have an MRC Clinician Scientist Fellowship and I am setting up a group at the Weatherall Institute of Molecular Medicine. In addition, I am an honorary consultant haematologist with the allogeneic transplant service in Oxford.
My research focuses on developing novel next generation sequencing-based methods for interrogating how the genome functions and leveraging this to develop methods of genome editing bone marrow derived stem cells. I have a particular interest in developing methods that allow the physical structure of DNA in the nucleus to be defined. With Jim Hughes and Doug Higgs I developed the Capture-C method. This technique lead to insights into how genes are controlled and I was awarded the RDM Graduate Prize for this project. I am also interested in using genome editing of bone marrow derived stem cells to treat disease. In particular, I am using my previous expertise in bioinformatics to and high throughput sequencing to develop new ways of defining off target effects from genome editing.
My research focuses on developing novel next generation sequencing-based methods for interrogating how the genome functions and leveraging this to develop methods of genome editing bone marrow derived stem cells. I have a particular interest in developing methods that allow the physical structure of DNA in the nucleus to be defined. With Jim Hughes and Doug Higgs I developed the Capture-C method. This technique lead to insights into how genes are controlled and I was awarded the RDM Graduate Prize for this project. I am also interested in using genome editing of bone marrow derived stem cells to treat disease. In particular, I am using my previous expertise in bioinformatics to and high throughput sequencing to develop new ways of defining off target effects from genome editing.
研究兴趣
论文共 260 篇作者统计合作学者相似作者
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ACS ES&T Airno. 4 (2024): 294-304
David Krige,Rahul C. Khanolkar,James A. Davies, Alexander T. Baker,Thomas A. Webb, Somayeh Shahreza,Hanni K. Uusi-Kerttula,Lucy M. Williams, Emma Henderson,Samantha L. Moore,Johanne M. Pentier,Bent K. Jakobsen,Alan L. Parker,David K. Cole,Andrew B. Gerry
Journal of Clinical Oncologyno. 16_suppl (2024)
AEROSOL SCIENCE AND TECHNOLOGYno. 4 (2024): 356-373
Trends in biochemical sciencesno. 2 (2024): 134-144
Nature geneticsno. 8 (2024): 1542-1543
Anna Appios,James Davies,Sofia Sirvent,Stephen Henderson,Sébastien Trzebanski,Johannes Schroth, Morven L Law, Inês Boal Carvalho, Marlene Magalhaes Pinto, Cyril Carvalho, Howard Yuan-Hao Kan, Shreya Lovlekar,Christina Major,Andres Vallejo,Nigel J Hall,Michael Ardern-Jones, Zhaoyuan Liu, Florent Ginhoux,Sian M Henson, Rebecca Gentek,Elaine Emmerson,Steffen Jung,Marta E Polak,Clare L Bennett
Science immunologyno. 99 (2024): eadp0344-eadp0344
CHEMICAL SCIENCEno. 8 (2024): 2963-2974
Michael J. Currie,James S. Davies,Mariafrancesca Scalise,Ashutosh Gulati,Joshua D. Wright,Michael C. Newton-Vesty,Gayan S. Abeysekera,Ramaswamy Subramanian,Weixiao Y. Wahlgren,Rosmarie Friemann,Jane R. Allison,Peter D. Mace,Michael D. W. Griffin,Borries Demeler,Soichi Wakatsuki,David Drew,Cesare Indiveri,Renwick C. J. Dobson,Rachel A. North
Sunniyat Rahman,Gianna Bloye,Nadine Farah,Jonas Demeulemeester,Joana R. Costa,David O’Connor,Rachael Pocock, Adam Turna, Lingyi Wang,SooWah Lee,Adele K. Fielding,Juliette Roels,Roman Jaksik,Malgorzata Dawidowska,Pieter Van Vlierberghe,Suzana Hadjur,Jim R. Hughes,James O.J. Davies,Alejandro Gutierrez,Michelle A Kelliher,Peter Van Loo,Mark A. Dawson,Marc R. Mansour
biorxiv(2024)
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作者统计
#Papers: 252
#Citation: 6952
H-Index: 47
G-Index: 77
Sociability: 7
Diversity: 3
Activity: 174
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