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Journal of physiology and pharmacology : an official journal of the Polish Physiological Society Journal

Papers
Although antidote development should proceed in an orderly fashion from observation, to experimental and safety studies, to clinical trials, this sequence is not always precisely followed. The development of fomepizole as an antidote for toxic alcohol and glycol poisoning is an e...
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Background:Lead toxicity continues to remain a concerning health problem for developing nations like Pakistan. Due to the lack of studies, we aim to highlight the clinical spectrum of lead poisoning in patients presenting to an urban-based tertiary care hospital in Pakistan. Meth...
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Alcohol provokes different molecular pathways contributing to a clinically significant neurotoxicity in different brain areas. Affected cognition in alcoholics can influence both daily life functioning and alcohol craving management abilities. Preventing alcohol-induced neurotoxi...
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Background: Poison Control Centre of Morocco (MPCC) plays a key role in promoting health. This study was aimed to demonstrate the role of the MPCC in improving public health and poisoning management. Methods: This was a retrospective study of poisoning cases reported to the MPCC ...
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Background: During the recent years, risk of lead poisoning has increased in Iranian’s opium users. A few researches showed that the most common route was ingestion of lead contaminated opium in these patients. However, data on lead poisoning through inhalation route in opium smo...
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Savitra Chintalapani, Madhuri Thanugundla, Fatima Sultana Syeda,Rakam Karthik, Y. Aparna, Imron Subhan
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Introduction: Methanol toxicity is a life-threatening condition which is rare in developed countries but common in developing countries. Bilateral putaminal necrosis and hemorrhage are potentially two lethal consequences of methanol toxicity which may be due to direct neurotoxici...
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Background:Cardiovascular effects of acute organophosphate (OP) poisoning are common. This study was aimed to assess the cardiovascular effects of OP poisoned patients in Nepal. Methods:This was a prospective hospital-based cross-sectional study of 115 acute OP poisoned patients ...
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Zohaib Abubaker,Maheen Nisar, Ahmed Jamshed, Mohammad Abbas, Kayhan Hashmi, Muhammad Arsalan
Background In Pakistan, most of the data on poisoning comes from scattered case series with data on poisoning mortality, and especially relating to people of lower socioeconomic status, lacking. We aim to shed some insight on the factors relating to poisoning mortality in Pakista...
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Background: Alcohol withdrawal syndrome (AWS) is one of the most serious complications associated with chronic alcoholism. Sudden deaths are not uncommon in AWS. In severe stages of AWS, delirium tremens (DT) occurs, which is characterized with agitation, global confusion, disori...
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Background: Patients presenting to Emergency department following consumption of toxic substances is not an uncommon phenomenon globally. It becomes essential for the Emergency physicians to have in-depth knowledge of all the toxic products available in their locality. In rural p...
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Mehrdad Ehterami
Background: The international drug abuse standards were achieved by review of a vast meta-analysis in the world and released 2 years ago in Vienna. Review of national programs in recent 20 years and conformity of them is the main objective of this presentation. Methods: Based on ...
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Devanur Rajashekhara Murthy Mahadeshwara Prasad, Abhilash Chennabasappa
Background: Paraquat poisoning is a medical emergency challenge due to its inherent severe toxicity and unavailability of specific antidote for it. In this paper, a series of patients who were treated according to a commonly used treatment flowchart are presented. Methods: This p...
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Background: AUDIT is constructed to be able to identify hazardous drinking and less severe alcohol-related problems. The original AUDIT was shown to have a cut-off score of 8 and above for identifying hazardous or harmful alcohol consumption. The aim of this study was to establis...
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Osareniro Osakue,Emmanuel Ileoma, Temitope Olusanya, Chioma Ndunaka, Fatima Lawal, Seyi Enitan,Esther Adejumo, Osayomore Osakue, Gideon Oluwaloye, Yusuf Yinusa
Background: Exposure to flour dust has been linked to the emergence of respiratory symptoms. This study assessed the levels of some inflammatory markers and hematological parameters among bakery workers exposed to flour dust in Ota, Nigeria. Methods: A total of 100 participants (...
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Background: To study the pattern of acute chemical and pharmaceutical poisoning in Ahmadabad, Gujarat, India. Methods: This was a prospective study of patients with chemical and pharmaceutical poisoning who were admitted to the emergency department of Civil Hospital Ahmadabad, fr...
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Background: Religious beliefs, access to alcohol and country rules clearly have impact on people's attitudes towards alcohol consumption. In this large study, sociological perspectives of people have been assessed about the effects of alcohol on some of common health problems. Me...
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Background: Pesticide poisoning is a common method of suicide attempt and less commonly accidental poisoning in Bangladesh. This review for the first time estimated the extent and characteristics of pesticide poisoning in Bangladesh and explored existing limitations in methodolog...
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Fazle Chowdhury,Mohammad Bari, Abdul Shafi,Abdul Ruhan,Mohammad Hossain, Sonia Chowdhury, Mohammad Hafiz
Background: Wasp stings are quite commonly observed in Bangladesh though they are under reported. However, rhabdomyolysis following multiple wasp stings is a rare entity. Case report: A middle aged physician was stung by a swarm of wasps at multiple sites of the body. He felt sev...
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Recently, I asked some prominent toxicologists in high income countries to contribute articles to inaugural issue of the newly established Asia Pacific Journal of Medical Toxicology (APJMT). I realized many of them seemed to be busy with other scientific engagements rather than p...
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