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    • World journal of critical care medicine Journal

    Papers
    Impact of High Dose Vitamin C on Platelet Function
    Bassem M Mohammed,Kimberly W Sanford,Bernard J Fisher,Erika J Martin,Daniel Contaifer,Urszula Osinska Warncke,Dayanjan S Wijesinghe,Charles E Chalfant,Donald F Brophy,Alpha A Fowler Iii,Ramesh Natarajan
    World journal of critical care medicine（2017）
    AIM:To examine the effect of high doses of vitamin C (VitC) on ex vivo human platelets (PLTs). METHODS:Platelet concentrates collected for therapeutic or prophylactic transfusions were exposed to: (1) normal saline (control); (2) 0.3 mmol/L VitC (Lo VitC); or (3) 3 mmol/L VitC (H...
    Cited16Views45
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    Role of Cerebrospinal Fluid Lactate in Diagnosing Meningitis in Critically Ill Patients
    Devraj Yadav,Omender Singh,Deven Juneja,Amit Goel,Sahil Kataria,Anisha Beniwal
    World journal of critical care medicine（2023）
    BACKGROUND:Meningitis is a life-threatening clinical condition associated with high mortality and morbidity. Early diagnosis and specific treatment may improve outcomes. Lack of specific clinical signs or tests make the diagnosis challenging. AIM:To assess the efficacy of cerebro...
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    Prediction of Hospital Mortality in Intensive Care Unit Patients from Clinical and Laboratory Data: A Machine Learning Approach
    Elena Caires Silveira,Soraya Mattos Pretti,Bruna Almeida Santos,Caio Fellipe Santos Corrêa,Leonardo Madureira Silva,Fabrício Freire de Melo
    World journal of critical care medicine（2022）
    BACKGROUND:Intensive care unit (ICU) patients demand continuous monitoring of several clinical and laboratory parameters that directly influence their medical progress and the staff's decision-making. Those data are vital in the assistance of these patients, being already used by...
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    Sequential Organ Failure Assessment Score is Superior to Other Prognostic Indices in Acute Pancreatitis
    Thomas Zheng Jie Teng,Jun Kiat Thaddaeus Tan,Samantha Baey,Sivaraj K Gunasekaran,Sameer P Junnarkar,Jee Keem Low,Cheong Wei Terence Huey,Vishal G Shelat
    World journal of critical care medicine（2021）
    BACKGROUND:Acute pancreatitis (AP) is a common surgical condition, with severe AP (SAP) potentially lethal. Many prognostic indices, including; acute physiology and chronic health evaluation II score (APACHE II), bedside index of severity in acute pancreatitis (BISAP), Glasgow sc...
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    Validation of the VitalPAC Early Warning Score at the Intermediate Care Unit
    Joost Dj Plate,Linda M Peelen,Luke Ph Leenen,Falco Hietbrink
    World journal of critical care medicine（2018）
    AIM To assess the performance and clinical relevance of the Early Warning Scoring (EWS) system at the Intermediate Care Unit (IMCU). METHODS This cohort study used all the VitalPAC EWS (ViEWS) scores collected during each nursing shift from 2014 through 2016 at the mixed surgical...
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    Ethical Publishing in Intensive Care Medicine: A Narrative Review
    Christian J Wiedermann
    World journal of critical care medicine（2016）
    Ethical standards in the context of scientific publications are increasingly gaining attention.A narrative review of the literature concerning publication ethics was conducted as found in PubMed, Google Scholar, relevant news articles, position papers, websites and other sources....
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    Should We Initiate Vasopressors Earlier in Patients with Septic Shock: A Mini Systemic Review
    Hang-Xiang Zhou,Chun-Fu Yang,He-Yan Wang,Yin Teng,Hang-Yong He
    World journal of critical care medicine（2023）
    Sepsis is defined as a life-threatening organ dysfunction caused by the dysregulated host response to infection. It is a complex syndrome and is characterized by physiologic, pathologic and biochemical abnormalities in response to an infection. Diagnosis of sepsis is based on his...
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    Point-of-care Ultrasound in a Pandemic: Practical Guidance in COVID-19 Units
    Himanshu Deshwal,Deepak Pradhan,Vikramjit Mukherjee
    World journal of critical care medicine（2021）
    The coronavirus disease 2019 (COVID-19) pandemic has stretched our healthcare system to the brink, highlighting the importance of efficient resource utilization without compromising healthcare provider safety. While advanced imaging is a great resource for diagnostic purposes, th...
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    Metabolic Theory of Septic Shock
    Jay Pravda
    World journal of critical care medicine（2014）
    Septic shock is a life threatening condition that can develop subsequent to infection.Mortality can reach as high as 80% with over 150000 deaths yearly in the United States alone.Septic shock causes progressive failure of vital homeostatic mechanisms culminating in immunosuppress...
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    Has Stewart Approach Improved Our Ability to Diagnose Acid-Base Disorders in Critically Ill Patients
    Fabio D Masevicius,Arnaldo Dubin
    World journal of critical care medicine（2015）
    The Stewart approach-the application of basic physical-chemical principles of aqueous solutions to blood-is an appealing method for analyzing acid-base disorders. These principles mainly dictate that pH is determined by three independent variables, which change primarily and inde...
    Cited21Views4
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    Impact of Perioperative Hyponatremia in Children: A Narrative Review
    Cheme Andersen,Arash Afshari
    World journal of critical care medicine（2014）
    For more than 50 years, hypotonic fluids (crystalloids) have been the standard for maintenance fluid used in children. In the last decade, several studies have evaluated the risk of hyponatremia associated with the use of hypotonic vs isotonic fluids, which has lead to an intense...
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    Effects of Mineralocorticoid Receptor Antagonists on Responses to Hemorrhagic Shock in Rats
    Kanako Yamamoto,Takashi Yamamoto,Masayuki Takamura,Soichiro Usui,Hisayoshi Murai,Shuichi Kaneko,Takumi Taniguchi
    World journal of critical care medicine（2018）
    AIM To evaluate the effects of mineralocorticoid receptor (MR) antagonists on mortality and inflammatory responses after hemorrhagic shock (HS) in rats. METHODS One hundred and two male Sprague–Dawley rats were randomly assigned to one of the following three groups: Control, spir...
    Cited1Views4
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    Arterial Vs Venous Blood Gas Differences During Hemorrhagic Shock
    Kristopher Burton Williams,Ashley Britton Christmas,Brant Todd Heniford,Ronald Fong Sing,Joseph Messick
    World journal of critical care medicine（2014）
    AIMTo characterize differences of arterial (ABG) and venous (VBG) blood gas analysis in a rabbit model of hemorrhagic shock.METHODSFollowing baseline arterial and venous blood gas analysis, fifty anesthetized, ventilated New Zealand white rabbits were hemorrhaged to and maintaine...
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    From Bronchiolitis Guideline to Practice: A Critical Care Perspective
    James A Lin,Andranik Madikians
    World journal of critical care medicine（2015）
    Acute viral bronchiolitis is a leading cause of admission to pediatric intensive care units, but research on the care of these critically ill infants has been limited. Pathology of viral bronchiolitis revealed respiratory obstruction due to intraluminal debris and edema of the ai...
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    Precision Medicine in Sepsis and Septic Shock: from Omics to Clinical Tools
    Juan Carlos Ruiz-Rodriguez,Erika P Plata-Menchaca,Luis Chiscano-Camón,Adolfo Ruiz-Sanmartin,Marcos Pérez-Carrasco,Clara Palmada,Vicent Ribas,Mónica Martínez-Gallo,Manuel Hernández-González,Juan J Gonzalez-Lopez,Nieves Larrosa,Ricard Ferrer
    World journal of critical care medicine（2022）
    Sepsis is a heterogeneous disease with variable clinical course and several clinical phenotypes. As it is associated with an increased risk of death, patients with this condition are candidates for receipt of a very well-structured and protocolized treatment. All patients should ...
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    New Pharmacological Approaches Against Chronic Bowel and Bladder Problems in Paralytics
    Pierre A Guertin
    World journal of critical care medicine（2016）
    Spinal cord injury (SCI) leads generally to an irreversible loss of sensory functions and voluntary motor control below injury level. Cures that could repair SCI and/or restore voluntary walking have not been yet developed nor commercialized. Beyond the well-known loss of walking...
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    Regional Dynamic Cerebral Autoregulation Across Anterior and Posterior Circulatory Territories: A Detailed Exploration and Its Clinical Implications
    Bahadar S Srichawla,Maria A Garcia-Dominguez
    World journal of critical care medicine（2024）
    Cerebral autoregulation (CA) is the mechanism that maintains stable cerebral blood flow (CBF) despite fluctuations in systemic blood pressure, crucial for brain homeostasis. Recent evidence highlights distinct regional variations in CA between the anterior (carotid) and posterior...
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    Reproducibility of Diaphragm Thickness Measurements by Ultrasonography in Patients on Mechanical Ventilation
    Ashesh Dhungana,Gopi Khilnani,Vijay Hadda,Randeep Guleria
    World journal of critical care medicine（2017）
    AIM:To prospectively evaluate the reproducibility of diaphragm thickness measurement by ultrasonography at the bedside by critical care physicians in patients on invasive mechanical ventilation.METHODS:In a prospective observational study of 64 invasively ventilated patients, dia...
    Cited26Views3
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    Frequency of Hepatic Steatosis and Its Association with the Pneumonia Severity Score on Chest Computed Tomography in Adult COVID-19 Patients
    Mehmet Tahtabasi,Tugrul Hosbul,Ergin Karaman,Yasin Akin,Nihat Kilicaslan,Mehmet Gezer,Fatih Sahiner
    World journal of critical care medicine（2021）
    BACKGROUND Recent studies of the coronavirus disease 2019 (COVID-19) demonstrated that obesity is significantly associated with increased disease severity, clinical outcome, and mortality. The association between hepatic steatosis, which frequently accompanies obesity, and the pn...
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    Diuretic Combinations in Critically Ill Patients with Respiratory Failure: A Systematic Review and Meta-Analysis
    Jean Maxime Côté, Nadir Goulamhoussen,Blaithin A McMahon,Patrick T Murray
    World journal of critical care medicine（2022）
    BACKGROUND In patients with respiratory failure, loop diuretics remain the cornerstone of the treatment to maintain fluid balance, but resistance is common.AIM To determine the efficacy and safety of common diuretic combinations in critically ill patients with respiratory failure...
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