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    • Immunotherapy Journal

    Papers
    Homophilic Antibodies As Immunotherapeutics
    Heinz Kohler
    Immunotherapy（2013）
    This review recalls the history of homophilic antibody discovery and adaptation for cancer immunotherapy. Homophilic antibodies are a rare type of murine monoclonal antibody produced by plasmacytomas. They are self-binding in solid-phase assays and, in solution, are in an equilib...
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    Validation of Immunogenic PASD1 Peptides Against HLA-A*24:02 Colorectal Cancer
    Joanne E. C. Soh,Nadiah Abu,Ismail Sagap,Luqman Mazlan,Azyani Yahaya,Muaatamarulain Mustangin,Tze S. Khoo,Sazuita Saidin,Muhiddin Ishak,Nurul S. Ab Mutalib,Rahman Jamal
    Immunotherapy（2019）
    Colorectal cancer is the third commonest malignancy in Asia including Malaysia. The immunogenic cancer-testis antigens, which are expressed in a variety of cancers but with limited expression in normal tissues except the testis, represent an attractive approach to improve treatme...
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    Low-dose Metronomic Gemcitabine Pretreatments Overcome the Resistance of Breast Cancer to Immune Checkpoint Therapy
    Xichen Zheng,Jiajie Kuai,Guanghui Shen
    Immunotherapy（2023）
    Aims: Immunotherapy has revolutionized cancer management. However, response to immunotherapy is heterogeneous. Thus, strategies to improve antitumor immune responses in resistant tumors, such as breast cancer, are urgently needed. Methods: Established murine tumors were treated w...
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    Antithymocyte Globulin-Induced Hemolytic Anemia and Thrombocytopenia after Kidney Transplantation
    T. de Nattes, L. Lelandais,I. Etienne,C. Laurent,D. Guerrot,D. Bertrand
    Immunotherapy（2018）
    Antithymocyte globulin is the most widely used lymphocyte-depleting treatment in kidney transplantation. In spite of the frequency of side effects, including anemia and thrombocytopenia, their pathophysiological mechanisms are not clearly established. Here, we report the case of ...
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    The Long-Term Efficacy of Cytokine-Induced Killer Cellular Therapy for Hepatocellular Carcinoma: a Meta-Analysis
    Jiaxue Wang,Tiantian Shen,Qi Wang,Tan Zhang,Lujin Li,Yu Wang,Yi Fang
    Immunotherapy（2019）
    Aim: The long-term efficacy of cytokine-induced killer cellular therapy for hepatocellular carcinoma patients after curative treatments remains controversial. Methods: A meta-analysis was conducted, and the outcomes were the recurrence rate and overall survival. Results: Eight ra...
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    Bone Marrow Transplantation in Epidermolysis Bullosa
    A. Abdul-Wahab,G. Petrof,J. A. McGrath
    Immunotherapy（2012）
    Epidermolysis bullosa (EB) is a heterogeneous group of inherited blistering skin diseases. Severe forms of EB are associated with increased morbidity and mortality, and there is currently no effective treatment. To combat severe complications of EB, such as chronic erosions, scar...
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    Development of Hepatitis Triggered by SARS-CoV-2 Vaccination in Patient with Cancer During Immunotherapy: a Case Report
    Angioletta Lasagna,Marco Vincenzo Lenti,Irene Cassaniti,Paolo Sacchi
    Immunotherapy（2022）
    Patients with cancer have a higher risk of severe COVID-19, and expert consensus advocates for COVID-19 vaccination in this population. Some cases of autoimmune hepatitis have been described after the administration of COVID-19 vaccine in the people in apparently good health. Imm...
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    Immunologic Treatment of Parkinson's Disease
    Joseph Jankovic
    Immunotherapy（2018）
    ImmunotherapyVol. 10, No. 2 EditorialImmunologic treatment of Parkinson's diseaseJoseph JankovicJoseph Jankovic*Author for correspondence: Tel: +1 713 798 6556; Fax: +1 713 798 6808; E-mail Address: josephj@bcm.edu; www.jankovic.org Distinguished Chair in Movement Disorders, Dire...
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    Immunotherapy in melanoma
    Emily Feld,Tara C Mitchell
    IMMUNOTHERAPY（2018）
    Immunotherapy has dramatically improved the prognosis for patients with melanoma and has become the cornerstone of treatment for those with advanced disease. The role of immunotherapy continues to expand with multiple new agents approved in the adjuvant as well as metastatic sett...
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    Imaging-calculated Splenic Volume is Associated with Response in Melanoma Patients Treated with Immunotherapy
    Mateus de Oliveira Taveira, Milton Jose Silva,Paula Nicole Vieira Barbosa Pinto
    IMMUNOTHERAPY（2023）
    Background: Predicting the roughly 50% of melanoma patients that will respond to immunotherapy is challenging. We tested if splenic volume could be a predictive biomarker. Methods: Splenic volume was measured by a semiautomated commercial software tool in pre- and post-treatment ...
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    Chimeric Antigen Receptor T Cells for the Treatment of Cancer and the Future of Preclinical Models for Predicting Their Toxicities
    Anja Wegner
    Immunotherapy（2017）
    Chimeric antigen receptor T-cell therapy has achieved highly promising results in clinical trials, particularly in B-cell malignancies. However, reports of serious adverse events including a number of patient deaths have raised concerns about safety of this treatment. Presently a...
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    New Targeted Therapies in Spondyloarthritis: What Are the Limits
    Daniel Wendling
    Immunotherapy（2019）
    "It would be interesting to acquire knowledge about predictive factors of good clinical response for each of these treatments. This would allow a more accurate decision on treatment initiation and a trend to personalized medicine. This may be achieved by retrospectively analyzing...
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    UV-induced Immunosuppressive and Anti-Inflammatory Actions: Mechanisms and Clinical Applications
    E. Dupont,L. Craciun
    Immunotherapy（2009）
    The introduction in 1974 of psoralens UVA (PUVA) therapy followed in 1987 by extracorporeal photopheresis (ECP) has launched UV light in medicine field. A significant number of potential mechanisms could be linked to the basic cellular UV action (i.e., DNA damage and subsequent c...
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    Is There Any Relationship Between Gene Expression of Tumor Antigens and CD4+T Cells in Multiple Myeloma
    Walter M. T. Braga,Bruna R. da Silva,Veruska L. F. Alves,Adriana B. Bortoluzo,Djordje Atanackovic,Gisele W. B. Colleoni
    Immunotherapy（2014）
    Aim: The present study aimed at correlating the expression of cancer/testis antigens (CTAs) with the expression of genes related to tumor-infiltrating T cells. Materials & methods: MAGE-C1/CT-7, MAGEA3/6, NY-ESO-1, LAGE-1 and GAGE expression were evaluated in 46 bone marrow multi...
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    Novel Immunotherapeutic Strategies for Pyelonephritis
    Thomas Tsaganos,Evangelos J. Giamarellos-Bourboulis
    Immunotherapy（2016）
    Acute pyelonephritis is an infection of the renal parenchyma and renal pelvis. When it is caused by a typical pathogen in an immunocompetent female patient with normal urinary tract, it is considered uncomplicated. In all other cases, sepsis is the most worrisome complication. In...
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    Targeting the T-cell Co-Stimulatory CD27/CD70 Pathway in Cancer Immunotherapy: Rationale and Potential
    Koen van de Ven,Jannie Borst
    Immunotherapy（2015）
    In 2013, cancer immunotherapy was named 'breakthrough of the year' based on the outcome of clinical trials with blocking antibodies to the T-cell co-inhibitory receptors CTLA-4 and PD-1. This success has emphasized that cytotoxic T-cell responses to cancer can occur, but are limi...
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    Immunotherapy for Head and Neck Cancer: Where Do We Go from Here
    Eric C. Ko,Glenn J. Hanna
    IMMUNOTHERAPY（2023）
    Tweetable abstract Immunotherapy for head and neck cancer shows promising new directions – and challenges ahead. What can we learn from recent trials to improve patient selection and optimize combination therapy?
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    Abrocitinib for the Treatment of Atopic Dermatitis
    Ana Maria Lé,Melinda Gooderham,Tiago Torres
    Immunotherapy（2023）
    Abrocitinib is an oral small molecule which selectively inhibits JAK1, modulating multiple cytokine pathways involved in atopic dermatitis. Both abrocitinib 200 mg and 100 mg reached efficacy results comparable to dupilumab and superior to placebo. Abrocitinib 200 mg was superior...
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    Beyond Immunosuppression: Reconsidering Indoleamine 2,3-Dioxygenase As a Pathogenic Element of Chronic Inflammation
    Alexander J. Muller,Laura Mandik-Nayak,George C. Prendergast
    Immunotherapy（2010）
    ImmunotherapyVol. 2, No. 3 EditorialFree AccessBeyond immunosuppression: reconsidering indoleamine 2,3-dioxygenase as a pathogenic element of chronic inflammationAlexander J Muller, Laura Mandik-Nayak and George C PrendergastAlexander J Muller, Laura Mandik-NayakLankenau Institut...
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    Baked Milk and Baked Egg Oral Immunotherapy
    Meng Chen,Michael Land
    Immunotherapy（2017）
    ImmunotherapyVol. 9, No. 15 EditorialBaked milk and baked egg oral immunotherapyMeng Chen & Michael LandMeng Chen*Author for correspondence: E-mail Address: Mec079@ucsd.edu Department of Medicine, Section on Allergy & Immunology, University of California, 8899 University City Lan...
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