基本信息
浏览量:0
职业迁徙
个人简介
Research Synopsis
Detailed Description: At the mature synapse, the presynaptic voltage-dependent calcium channels co-localize with synaptic elements at the active zone. However, the mechanisms underlying development of presynaptic architecture during synapse formation are largely unknown. Since synaptogenesis between identified pre- and postsynaptic neurons in a mammalian system is often difficult to study at a single cell level, our laboratory uses Lymnaea synapse as a model to determine cellular and molecular mechanisms by which voltage-dependent calcium channels and synaptic structural proteins are targeted to specific synaptic sites during synapse formation and synaptic plasticity.
Detailed Description: At the mature synapse, the presynaptic voltage-dependent calcium channels co-localize with synaptic elements at the active zone. However, the mechanisms underlying development of presynaptic architecture during synapse formation are largely unknown. Since synaptogenesis between identified pre- and postsynaptic neurons in a mammalian system is often difficult to study at a single cell level, our laboratory uses Lymnaea synapse as a model to determine cellular and molecular mechanisms by which voltage-dependent calcium channels and synaptic structural proteins are targeted to specific synaptic sites during synapse formation and synaptic plasticity.
研究兴趣
论文共 195 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Guangmin Yao, Matthew R. Parris, W. Cedric Kuo, Peter Porzgen, Brandi Castillo, Evan S. Mason, Andres Chinchilla, Junhao Huang,Sayuri Suzuki, Rylee Ross, Ellis Akana, Savana Vander Schuit,
JOURNAL OF NATURAL PRODUCTSno. 4 (2024): 783-797
Mengjia Huang, Chun Hin Chow,Akshay Gurdita,Hidekiyo Harada, Victor Q. B. Pham Truong,Sarah Eide,Hong-Shuo Sun,Zhong-Ping Feng,Philippe P. Monnier,Valerie A. Wallace,Shuzo Sugita
Communications Biologyno. 1 (2024): 1-14
Acta pharmacologica Sinica (2024)
Cell Calcium (2024): 102886-102886
Cell & Bioscienceno. 1 (2024): 1-20
ACTA PHARMACOLOGICA SINICA (2024)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn