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个人简介
I am a chemist by training and also a biomedical engineer skilled in many fields of engineering and science,ranging from protein engineering to chemistry to optics. I am the key inventor of genetically encoded calcium ion indicators, GECO family, as well as genetically encoded voltage indicators, QuasAr. Both tools have been distributed and used by thousands of labs worldwide. I also co-invented a transformative imaging tool, called Expansion Pathology (ExPath), which enables nanoscale imaging of paraffin-embedded,hematoxylin and eosin (H&E)-stained, and/or other biopsy samples of human tissues. The mission of my CMU group is to develop and apply new tools to establish biomolecule atlas of the brain,tumor, and other complex biological systems and interrogate the biological mechanisms, fostering new discovery, new diagnosis, and therapeutics in the long term.Currently, we are developing a suite of tools that enable highly multiplex molecular spatial profiling in 3-D large biological systems with nanoscale precision. My multidisciplinary research program tackles intractable problems in the fields of biology,pathology, and medicine by collaborating with biologists, chemists, computer scientists, and clinicians in dozens of labs in the US and overseas to bring new technologies to fruition, aiming to distribute new tools to thousands of research groups around the world.
研究兴趣
论文共 63 篇作者统计合作学者相似作者
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Pablo A Valdes,Chih-Chieh Jay Yu, Jenna Aronson, Debarati Ghosh,Yongxin Zhao,Bobae An,Joshua D Bernstock,Deepak Bhere,Michelle M Felicella,Mariano S Viapiano,Khalid Shah,E Antonio Chiocca,
Nature nanotechnologyno. 4 (2023): 324-325
Journal of visualized experiments : JoVE (2023)
Zhangyu Cheng,Caroline Stefani, Thomas Skillman,Aleksandra Klimas, Aramchan Lee,Emma F DiBernardo,Karina Mueller Brown, Tatyana Milman, Yuhong Wang,Brendan R Gallagher,Katherine Lagree,Bhanu P Jena,
Advanced science (Weinheim, Baden-Wurttemberg, Germany)no. 30 (2023): n/a-n/a
Zhangyu Cheng,Caroline Stefani, Thomas Skillman,Aleksandra Klimas, Aramchan Lee,Emma F DiBernardo, Karina M Brown, Tatyana Milman,Brendan R Gallagher,Katherine Lagree,Bhanu P Jena, Jose Pulido,
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canadano. 29 Suppl 1 (2023): 994-994
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canadano. Supplement_1 (2023): 999-1001
NEUROPSYCHOPHARMACOLOGY (2022): 376-376
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