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Miao Lab research mainly focuses on studying the mechanisms of actin assembly in polarized fungal growth and plant immunity. Miao Lab interested in how diverse extracellular and intracellular signals regulate actin assembly underlying diverse physiological and pathological processes in eukaryotic cells. Actin filament assembly contributes to the multiple cellular pathways pleiotropically, by its dynamic assembly and disassembly upon cellular needs and specific stimuli, such as the activation of polarized cell growth or the host immune responses during defense mechanisms against pathogenic attack. In the much crowd intracellular environment, actin-binding proteins (ABPs) precisely regulate the dynamics assembly and re-organization of actin networks, in cooperative and competitive manners. We are particularly interested in how the intrinsically disordered regions (IDRs) of ABPs perceive the signals to trigger re-organization of actin assembly, by regulating the protein dynamics, protein conformation, and protein-protein interactions, via interdisciplinary approaches, such as biochemical assay, advanced cell imaging, genetic approaches.
Miao Lab research mainly focuses on studying the mechanisms of actin assembly in polarized fungal growth and plant immunity. Miao Lab interested in how diverse extracellular and intracellular signals regulate actin assembly underlying diverse physiological and pathological processes in eukaryotic cells. Actin filament assembly contributes to the multiple cellular pathways pleiotropically, by its dynamic assembly and disassembly upon cellular needs and specific stimuli, such as the activation of polarized cell growth or the host immune responses during defense mechanisms against pathogenic attack. In the much crowd intracellular environment, actin-binding proteins (ABPs) precisely regulate the dynamics assembly and re-organization of actin networks, in cooperative and competitive manners. We are particularly interested in how the intrinsically disordered regions (IDRs) of ABPs perceive the signals to trigger re-organization of actin assembly, by regulating the protein dynamics, protein conformation, and protein-protein interactions, via interdisciplinary approaches, such as biochemical assay, advanced cell imaging, genetic approaches.
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论文共 82 篇作者统计合作学者相似作者
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Chee San Tong,Maohan Su,He Sun, Xiang Le Chua,Ding Xiong, Su Guo, Ravin Raj, Nicole Wen Pei Ong, Ann Gie Lee,Yansong Miao,Min Wu
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2024): 1261117-1261117
bioRxiv : the preprint server for biology (2024)
The EMBO journalno. 9 (2024): 1898-1918
CELL RESEARCH (2023)
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Acta biochimica et biophysica Sinicano. 7 (2023): 1064-1074
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Zhu Qiao,Edwin R. Lampugnani,Xin-Fu Yan,Ghazanfar Abbas Khan, Saw Wuan Geok, Patrick Hannah, Feng Qian,Jacob Calabria,Yansong Miao, Gerhard Grüber,Staffan Persson,Yong-Gui Gao
Acta Crystallographica Section A Foundations and Advancesno. a2 (2023)
Chee San Tong,Maohan Su,He Sun, Xiang Le Chua, Su Guo, Ravinraj S/O Ramaraj, Ong Nicole Wen Pei, Ann Gie Lee,Yansong Miao,Min Wu
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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