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Professor Rades has developed an international reputation for his research in the physical characterization of drugs solid dosage forms as well as in vaccine delivery using nanoparticulate systems (both polymeric and lipid based). Professor Rades has published more than 400 papers in international peer review journals as well as several book chapters and patents and one book. He is an Editor of the Journal of Pharmaceutical Sciences and the European Journal of Pharmaceutics and Biopharmaceutics and an Associate Editor of the Journal of Pharmacy and Pharmacology. He holds an honorary doctorate of Åbo Akademie University, Finland, a visiting professorship at the Department of Medicine at the University of Adelaide, Australia and an honorary professorship at the University of Otago, New Zealand. He is an Eminent Fellow of the Academy of Pharmaceutical Sciences (UK) and a Fellow of the New Zealand Institute of Chemistry. Professor Rades has successfully supervised more than 75 PhD students. He was awarded the New Zealand Tertiary Teaching Excellence Award for Sustained Excellence (2005) for his undergraduate and postgraduate teaching activities.
His research interests include the solid state of drugs and dosage forms, and nanoparticles as delivery systems for drugs and vaccines. Research in both areas aims to improve drug therapy through appropriate formulation and characterisation of medicines and to increase understanding of the physico-chemical properties of drugs and medicines. His research combines physical, chemical, and biological sciences and technology to optimally formulate drugs and vaccines for human and veterinary uses.
Center involvements
Examples: Leo Foundation: LEO Foundation Center for Cutaneous Drug Delivery (LFCCDD): 40 mio DKK, 2017-2027; Role: PI for Formulation (15 mio DKK).
IMI EU consortium: Biopharmaceutical Tools for Oral Drug Delivery (OrBiTo) (10 big Pharma companies, 10 European universities and 2 SMEs). €10.6 mio, 2012-2017; Role: Task Leader (€0.75 mio).
Villum Kann Rasmussen Centre of Excellence “NanoMechanical Sensors” (Namec) in collaboration with DTU Nanotech. 28 mio DKK, 2009-14; Role: Task Leader (6 mio DKK).
A short summary of research interests
My whole research career, both in academia and industry (see employment record) has always focussed on improving drug delivery systems. The exact topics of course have shifted over the years, and span from colloidal delivery systems (including liposomal and other liquid crystalline systems, polymeric and lipid nanoparticles for drug and vaccine delivery) to solids state dosage forms, including polymorphic drugs and amorphous drugs delivery systems. The work is strongly based on a physicochemical underpinning of these enabling formulations, as well as a deep and thorough analytical characterisation and understanding of such systems. Work in recent years has increasingly used thermal analytical, diffractometric, and spectroscopic methods, both quantitatively and structurally. An additional focus has always been the preparative aspects of such enabling formulations, including technologies such as spray drying, melt extrusion, mechano-chemical activation, tabletting, encapsulation etc.
His research interests include the solid state of drugs and dosage forms, and nanoparticles as delivery systems for drugs and vaccines. Research in both areas aims to improve drug therapy through appropriate formulation and characterisation of medicines and to increase understanding of the physico-chemical properties of drugs and medicines. His research combines physical, chemical, and biological sciences and technology to optimally formulate drugs and vaccines for human and veterinary uses.
Center involvements
Examples: Leo Foundation: LEO Foundation Center for Cutaneous Drug Delivery (LFCCDD): 40 mio DKK, 2017-2027; Role: PI for Formulation (15 mio DKK).
IMI EU consortium: Biopharmaceutical Tools for Oral Drug Delivery (OrBiTo) (10 big Pharma companies, 10 European universities and 2 SMEs). €10.6 mio, 2012-2017; Role: Task Leader (€0.75 mio).
Villum Kann Rasmussen Centre of Excellence “NanoMechanical Sensors” (Namec) in collaboration with DTU Nanotech. 28 mio DKK, 2009-14; Role: Task Leader (6 mio DKK).
A short summary of research interests
My whole research career, both in academia and industry (see employment record) has always focussed on improving drug delivery systems. The exact topics of course have shifted over the years, and span from colloidal delivery systems (including liposomal and other liquid crystalline systems, polymeric and lipid nanoparticles for drug and vaccine delivery) to solids state dosage forms, including polymorphic drugs and amorphous drugs delivery systems. The work is strongly based on a physicochemical underpinning of these enabling formulations, as well as a deep and thorough analytical characterisation and understanding of such systems. Work in recent years has increasingly used thermal analytical, diffractometric, and spectroscopic methods, both quantitatively and structurally. An additional focus has always been the preparative aspects of such enabling formulations, including technologies such as spray drying, melt extrusion, mechano-chemical activation, tabletting, encapsulation etc.
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Physical chemistry chemical physics : PCCP (2024)
European Journal of Pharmaceutics and Biopharmaceuticspp.114266-114266, (2024)
A. L. C. S. Nascimento, I. C. B. Martins, L. Sposito, G. Morais-Silva, J. L. Duarte,T. Rades, M. Chorilli
PHARMACEUTICSno. 1 (2024): 67
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