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个人简介
Steven Carr is senior director of proteomics at the Broad Institute of MIT and Harvard, where he is also an institute scientist. He is internationally recognized as a leader in the development of novel proteomics methods and in their application in biology, chemistry, and medicine.
Carr and his group of staff scientists and postdoctoral fellows collaborate with scientists throughout the Broad Institute community (comprised of MIT, Harvard University Faculty of Arts and Sciences, Harvard Medical School, and the 17 Harvard-affiliated hospitals) to apply state-of-the-art proteomics technology to address compelling questions in biology, chemistry, and clinical medicine.
Research in his laboratory focuses on developing and applying new technologies to quantify proteins and their modifications and interaction partners in tissues, cells, and biofluids with high sensitivity and specificity; improving informatics for peptide and protein assignment using mass spectrometry (MS) data; and integration of MS-derived data with genomic data to understand disease biology and drug effects. The group also has a major focus on the discovery and quantitative verification of biomarkers for major diseases including cancer and cardiovascular and infectious diseases, as well as pharmacodynamics markers of drug response.
Prior to returning to academia in 2004, Carr held scientific leadership positions at GlaxoSmithKline where he was the director of computational and structural sciences and at Millennium Pharmaceuticals where he was senior director of protein science and technology. Carr has more than 300 publications on the development and use of proteomics and biological mass spectrometry. He is deputy editor of Molecular and Cellular Proteomics, the leading journal in the field of proteomics.
Carr and his group of staff scientists and postdoctoral fellows collaborate with scientists throughout the Broad Institute community (comprised of MIT, Harvard University Faculty of Arts and Sciences, Harvard Medical School, and the 17 Harvard-affiliated hospitals) to apply state-of-the-art proteomics technology to address compelling questions in biology, chemistry, and clinical medicine.
Research in his laboratory focuses on developing and applying new technologies to quantify proteins and their modifications and interaction partners in tissues, cells, and biofluids with high sensitivity and specificity; improving informatics for peptide and protein assignment using mass spectrometry (MS) data; and integration of MS-derived data with genomic data to understand disease biology and drug effects. The group also has a major focus on the discovery and quantitative verification of biomarkers for major diseases including cancer and cardiovascular and infectious diseases, as well as pharmacodynamics markers of drug response.
Prior to returning to academia in 2004, Carr held scientific leadership positions at GlaxoSmithKline where he was the director of computational and structural sciences and at Millennium Pharmaceuticals where he was senior director of protein science and technology. Carr has more than 300 publications on the development and use of proteomics and biological mass spectrometry. He is deputy editor of Molecular and Cellular Proteomics, the leading journal in the field of proteomics.
研究兴趣
论文共 118 篇作者统计合作学者相似作者
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Molecular & cellular proteomics : MCPno. 12 (2023): 100665-100665
Jennifer G Abelin,Erik J Bergstrom,Keith D Rivera,Hannah B Taylor,Susan Klaeger, Charles Xu, Eva K Verzani, C Jackson White, Hilina B Woldemichael, Maya Virshup,Meagan E Olive, Myranda Maynard,
Elisabet Manasanch,Hannah Taylor, Gabrielle M Hernandez, Eva K Verzani,Claudia Ctortecka, David A Berrios Nolasco,Karl R Clauser,Namrata D Udeshi,Jennifer G Abelin,Steven A Carr
Journal for ImmunoTherapy of Cancerno. Suppl 2 (2023)
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Cancer Researchno. 5_Supplement (2023): P5-02
Nora Schmidt,Sabina Ganskih,Yuanjie Wei, Alexander Gabel,Sebastian Zielinski,Hasmik Keshishian,Caleb A Lareau,Liv Zimmermann,Jana Makroczyova, Cadence Pearce,Karsten Krey,Thomas Hennig,
Cellno. 22 (2023): 4834-4850.e23
Jinjin Xu,Lingjia Kong, Blayne A Oliver,Bihua Li,Elizabeth A Creasey,Gaelen Guzman,Monica Schenone,Kimberly L Carey,Steven A Carr,Daniel B Graham,Jacques Deguine,Ramnik J Xavier
Cell reportsno. 7 (2023): 112708-112708
Taylor Hanta Nagai, Chrissy Hartigan,Taiji Mizoguchi,Haojie Yu,Amy Deik,Kevin Bullock, Yanyan Wang, Debra Cromley,Monica Schenone,Chad A Cowan,Daniel J Rader,Clary B Clish,
Communications biologyno. 1 (2023): 1298-1298
Neuro-Oncologyno. Supplement_1 (2022): 126-126
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