基本信息
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职业迁徙
个人简介
Key Research Interests
Much of the work undertaken in the Carding research group based at IFR focuses on understanding the mechanisms of intestinal microbial tolerance and the role that microbe-host cross talk plays in establishing and maintaining gut health and in gut disease. Current research interests are, defining the link between the mucosal immune system, dendritic cells (DC) and lipid metabolism using a novel experimental model of obesity, the role autophagy plays in intestinal epithelial cell homeostasis, barrier function and mucosal immune responses to commensal and pathogenic microbes, the nature of mucosal immune cell (iIEL)-microbiota interactions in establishing and maintaining a healthy intestinal microbiome while mounting immediate response to food-borne pathogens, regulation of epithelial tight junctions and the maintenance of intestinal barrier function, interkingdom macromolecule exchange in microbe-host crosstalk and the establishment of mutualism in the GI-tract, development of novel strategies to treat and prevent chronic intestinal inflammation and IBD using SMART bacteria and novel foods, immune tolerance and implant rejection and, immunosenescence and diet.
Much of the work undertaken in the Carding research group based at IFR focuses on understanding the mechanisms of intestinal microbial tolerance and the role that microbe-host cross talk plays in establishing and maintaining gut health and in gut disease. Current research interests are, defining the link between the mucosal immune system, dendritic cells (DC) and lipid metabolism using a novel experimental model of obesity, the role autophagy plays in intestinal epithelial cell homeostasis, barrier function and mucosal immune responses to commensal and pathogenic microbes, the nature of mucosal immune cell (iIEL)-microbiota interactions in establishing and maintaining a healthy intestinal microbiome while mounting immediate response to food-borne pathogens, regulation of epithelial tight junctions and the maintenance of intestinal barrier function, interkingdom macromolecule exchange in microbe-host crosstalk and the establishment of mutualism in the GI-tract, development of novel strategies to treat and prevent chronic intestinal inflammation and IBD using SMART bacteria and novel foods, immune tolerance and implant rejection and, immunosenescence and diet.
研究兴趣
论文共 274 篇作者统计合作学者相似作者
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Rokas Juodeikis,Carlo Martins,Gerhard Saalbach, Jake Richardson,Todor Koev, Dave J. Baker,Marianne Defernez,Martin Warren,Simon R. Carding
JOURNAL OF EXTRACELLULAR VESICLESno. 1 (2024): e12406-e12406
Frontiers in Microbiology (2024): 1353539-1353539
FRONTIERS IN MICROBIOLOGY (2024)
Microbiology resource announcementsno. 3 (2023)
medRxiv (Cold Spring Harbor Laboratory) (2023)
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Gastroenterologyno. 6 (2023): S435-S435
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Biomicrofluidicsno. 5 (2023): 054104-054104
Amisha Modasia,Emily Jones, L. Marie‐Pascale Martel, Hélène Louvel, Pierre‐Olivier Couraud,L. Ashley Blackshaw,Simon R. Carding
Journal of extracellular biologyno. 7 (2023)
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