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个人简介
Dr. Magness’ research is focused on the basic biology of intestinal stem cells, the genes that control their behavior, and translational approaches to stem cell based therapies for human disease and injury of the intestine. Furthermore his research focuses on elucidating genetic mechanisms underlying stemness and developing translational models to establish a finer understanding of stem cell-driven regeneration dynamics in homeostasis and injury. Using a combination of genetic mouse models and micro-frabricated bioengineered platforms, Dr. Magness’ team is exploiting the self-renewal capacity and multi-potency of ISCs to develop long-term ex vivo models of the intestine and colon with primary tissues. These biomimetic models offer new solutions for compound screening and cell-based therapies
Research Interests
Stem Cell Biology
Niche Dynamics
Tissue Engineering
Biomimetic Scaffolds
Single-Cell Biology
Stem cell maintenance and differentiation
Single cell analytics
High-throughput biomimetic culture platforms
研究兴趣
论文共 135 篇作者统计合作学者相似作者
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Kristina R. Rivera,R. Jarrett Bliton,Joseph Burclaff,Michael J. Czerwinski,Jintong Liu, Jessica M. Trueblood,Caroline M. Hinesley,Keith A. Breau,Halston E. Deal, Shlok Joshi,Vladimir A. Pozdin, Ming Yao,
Cellular and Molecular Gastroenterology and Hepatologyno. 5 (2023): 823-846
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Deniz Coskuner,James B. Collins, Quinn Fong, Meredith J. Zeller, Andrew Lucas, Benyam Muluneh,Scott T. Magness, Aadra P. Bhatt
Gastroenterologyno. 6 (2023): S-472
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Meryem T. Ok,Jintong Liu,R. Jarrett Bliton,Caroline M. Hinesley, Ekaterina Ellyce San T. Pedro,Keith A. Breau, Ismael Gomez-Martinez,Joseph Burclaff,Scott T. Magness
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGYno. 4 (2023): G262-G280
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGYno. 4 (2023): G262-G280
Michael J Cotton,Pablo Ariel, Kaiwen Chen, Vanessa A Walcott, Michelle Dixit,Keith A Breau,Caroline M Hinesley,Kasia Kedziora,Cynthia Y Tang, Anna Zheng,Scott T Magness,Joseph Burclaff
bioRxiv : the preprint server for biology (2023)
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Gastroenterologyno. 6 (2023): S-130
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Amanda L Ziegler,Madison L Caldwell, Sara E Craig,Emily A Hellstrom, Anastasia E Sheridan,Melissa S Touvron,Tiffany A Pridgen,Scott T Magness,Jack Odle,Laurianne Van Landeghem,Anthony T Blikslager
biorxiv(2023)
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