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His research is currently focused on single molecule and single cell biophysics, and was initially concentrated on nanotechnology and solid-state physics. He has pioneered the use of carbon nanotubes as electronic devices, establishing the first carbon nanotube wire and transistor. Using novel single-molecule biophysics approaches, he discovered how various chaperones fold protein chains, and suppress the protein aggregation that underlies numerous ageing related pathologies. This work is currently extended to visualize chaperone-ribosome interactions and (ubiquitin mediated) protein degradation. He developed various approaches to reveal various cellular growth phenomena, ranging from stochasticity in metabolic networks to spatial competition between bacterial strains, and is increasingly focused on cellular dynamics within organoid systems. His work has appeared in a range of journals including Nature and Science (14 papers)
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论文共 145 篇作者统计合作学者相似作者
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Methods in molecular biology (Clifton, N.J.) (2024): 57-67
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Journal of the American Chemical Societyno. 28 (2023): 15188-15196
Florian Wruck,Mario J. Avellaneda, Maham Naqvi,Eline J. Koers, Katharina Till, Liza Gross,Fatemeh Moayed, Arlène Roland,Laurens W H J Heling,Alireza Mashaghi,Sander J. Tans
Royal Society of Chemistry eBookspp.278-318, (2023)
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Selami Baglamis,Vivek M. Sheraton, Debora Meijer,Haibin Qian,Ron A. Hoebe,Kristiaan J Lenos, Max A. Betjes, Max A. Betjes,Sander Tans,Jeroen van Zon,Louis Vermeulen,Przemek M. Krawczyk
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Tanja I. Kuhm, Luca Gross, Cecilia de Agrela Pinto,Stefan T. Huber, Clemence Taisne, Evdokia A. Giannopoulou,Els Pardon,Jan Steyaert,Sander J. Tans,Arjen J. Jakobi
biorxiv(2023)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Cell Reportsno. 10 (2023): 113284-113284
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