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Research Interests:
The Zandstra lab is interested in how individual cells form complex tissues and organs. His research focuses on understanding multiscale interactions between cells, and the influence of these interactions on internal regulatory control networks, and the external microenvironment that shapes cell fate and functional tissue development. His team is developing mathematical models of interactions between cellular regulatory networks and their local microenvironment, and using model predictions to guide the design of engineered niches and synthetic cells that detect, select and control functional tissue development from adult and pluripotent stem cells. These discoveries will elucidate the process of multicellular organization into complex functional tissues and enable production of therapeutically relevant cell types, with a particular focus on the blood cell forming system.
The Zandstra lab is interested in how individual cells form complex tissues and organs. His research focuses on understanding multiscale interactions between cells, and the influence of these interactions on internal regulatory control networks, and the external microenvironment that shapes cell fate and functional tissue development. His team is developing mathematical models of interactions between cellular regulatory networks and their local microenvironment, and using model predictions to guide the design of engineered niches and synthetic cells that detect, select and control functional tissue development from adult and pluripotent stem cells. These discoveries will elucidate the process of multicellular organization into complex functional tissues and enable production of therapeutically relevant cell types, with a particular focus on the blood cell forming system.
研究兴趣
论文共 160 篇作者统计合作学者相似作者
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GEN BIOTECHNOLOGYno. 2 (2023): 106-119
Laura N Stankiewicz,Fabio MV Rossi,Peter W Zandstra,Kevin Salim, Emily A Flaschner,Yu Xin Wang,John M Edgar, Bruce ZB Lin,Grace C Bingham, Matthew C Major,Ross D Jones,Helen Blau,
bioRxiv : the preprint server for biology (2023)
Bin Li, Daniel Rodrigo-Torres,Carl Pelz,Brendan Innes,Pamela Canaday, Sunghee Chai,Peter Zandstra,Gary D Bader,Markus Grompe
bioRxiv : the preprint server for biology (2023)
Yale S. Michaels, Matthew C. Major, Becca Bonham-Carter, Jingqi Zhang,Tiam Heydari,John M. Edgar,Laura Greenstreet,Roser Vilarrasa-Blasi, Seungjoon Kim,Elizabeth L. Castle,Aden Forrow, M Iliana Ibanez-Rios,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Cytotherapyno. 6 (2023): S220-S220
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