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In the laboratory we seek to address these issues by combining new experimental protocols utilizing the power of quantitative proteomics to identify sorting complexes and achieve an unbiased global analysis of the cargoes that they sort. In combining these molecular approaches with in vivo studies in model organisms and collaborative genetic analysis of patient cohorts, our research aims to define the underlying defects in endosomal sorting and signaling that occur in human disease.
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论文共 193 篇作者统计合作学者相似作者
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Rebeka Butkovič, Alexander P Walker,Michael D Healy,Kerrie E McNally, Meihan Liu,Kohji Kato,Brett M Collins,Peter J Cullen
biorxiv(2024)
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCESno. 1899 (2024): 20220376-20220376
Joshua Greig,George Thomas Bates, Daowen Ivanna Yin,Boris Simonetti,Peter J Cullen,Frances M. Brodsky
biorxiv(2024)
Philosophical transactions of the Royal Society of London. Series B, Biological sciencesno. 1899 (2024): 20220372-20220372
biorxiv(2023)
Jiahe Lu, Alisa Veler,Boris Simonetti,Timsse Raj, Po Han Chou,Stephen J Cross, Alexander M Phillips,Xiongtao Ruan,Lan Huynh,Andrew W Dowsey,Dingwei Ye,Robert F Murphy,
bioRxiv : the preprint server for biology (2023)
Jiahe Lu, Alisa Veler,Boris Simonetti,Timsse Raj, Po Han Chou,Stephen J. Cross,Alexander M. Phillips,Xiongtao Ruan,Lan Huynh,Andrew W. Dowsey,Dingwei Ye,Robert F. Murphy,
CELLSno. 21 (2023): 2558-2558
Michael D. Healy, Kerrie E. McNally,Rebeka Butkovic, Molly Chilton,Kohji Kato, Joanna Sacharz, Calum McConville,Edmund R.R. Moody, Shrestha Shaw, Vicente J. Planelles-Herrero,Sathish K.N. Yadav, Jennifer Ross,
biorxiv(2023)
Acta Crystallographica Section A Foundations and Advancesno. a2 (2023)
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