基本信息
浏览量:1
职业迁徙
个人简介
I no longer run an experimental lab, but am continuing various research activities. These include some projects using computer- (and even paper-) based meta-analysis of data from other sources, and appropriate simulations. I also have some continuing collaborations with others who are doing experimental work. I still teach on the Applied Biocatalysis module of the inter-university (IBioIC) MSc in Industrial Biotechnology.
My research interests are mostly related to the application of biological catalysts (enzymes or whole cells) in industrial processes. Rather than being focussed on specific products, I try to concentrate on general problems relevant to a range of actual and potential processes. I favour such strategic research as I would like to think that my work has relevance to a known field of application. However, I usually prefer a relatively fundamental approach, in the hope of finding the most generic solutions through proper understanding of the systems involved. Most of the research involves a physico-chemical approach to the systems, particularly using principles of thermodynamics and kinetics. Following my formal retirement in September 2016, I no longer run my own experimental laboratory. However I am continuing research in collaboration with others who do have experimental facilities, as well as working on data analysis, simulation and related styles of research.
The problems that are important in this area, as in so many others, are best tackled with a multi-disciplinary approach. I believe that my experience is a good basis for the application of knowledge from a wide range of relevant disciplines to these problems. This also means that much of my research is collaborative, often involving people from other backgrounds, particularly bioscience and process engineering, both at Strathclyde and elsewhere.
For many years my main area of work was on biocatalysts acting in low water media, particularly those based predominantly on organic liquids. As recently as the 1980s, textbooks still said that enzymes acted only in dilute aqueous solution, but it is now clear that low-water media can be used successfully, under appropriate conditions. Furthermore, these systems offer attractions for some industrial processes: particularly higher reactant content/concentration and the use of readily available hydrolytic enzymes to catalyse synthetic reactions. My main past contribution has been related to the role of the small amounts of water still present. I introduced the use of the thermodynamic water activity to characterise multi- phase systems of this type, and have studied its effects, measurements and control. The usefulness of this parameter is now widely accepted.
研究兴趣
论文共 168 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATIONno. 4 (2022): 352-353
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn