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My laboratory is interested in understanding the role of nuclear receptors in cancer progression and metastasis, particularly in melanoma, glioblastoma and, more recently, hepatocellular carcinoma. We also investigate the role of repetitive elements in the functioning of tumoral cells with emphasis in normal and tumor cell differentiation and pluripotency. The functional interaction of these processes with senescence and tissue regeneration is also a major scientific interest of the group. We use Genetics, Molecular and Cellular Biology and omics methodologies in cellular models, transgenic animal and human tumor biopsies. A major effort is dedicated to collaborate with the Molecular Pathology and Liver transplant Units of the Medical Hospital. We believe that our research is relevant not only to acquire knowledge about the mechanisms driving tumorigenesis and metastatic dissemination but also to human health and to cancer diagnosis and therapy
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International journal of molecular sciencesno. 6 (2023): 5550-5550
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